Mechanical properties of a scaffold play an important role in its in vivo performance in bone tissue engineering, due to the fact that implanted scaffolds are typically subjected to stress including compression, tension, torsion, and shearing. Unfortunately, not all the materials used to fabricate scaffolds are strong enough to mimic native bones. Extensive research has been conducted in order ...

introduction of the metallic nanoparticles (nps) in the bulk glass received a large interest due to their versatile applications. the effect of silver nps on optical properties of the eu3+-doped zinc tellurite glasses is presented for the first time. glass samples are prepared by melt-quenching technique. the surface plasmon absorption bands of silver nps are recorded in the visible region. the...

INTRODUCTION This study aimed to evaluate the potential applications of polycaprolactone (PCL)/submicron bioactive glass (smBG) hybrid composites for pulp and dentin tissue regeneration. METHODS PCL/smBG hybrid composites were made with novel monodispersive bioactive glass submicrospheres, and pure PCL and bioactive glass samples were used as controls. Surface characteristics were assessed by...

Responses of mesenchymal stem cells (MSCs) cultured with zinc-added (2 and 5%) bioactive glass granules were evaluated in terms of cell growth and osteogenic differentiation. MSCs were cultured with different quantities (3, 10 and 30) of glass granules for up to 21 days in the osteogenic medium. Cell growth was stimulated by a small quantity of glasses, particularly those that contained zinc. O...

In this paper synthesis and characterization of a bioactive calcium phosphate glass-ceramic is presented, synthesized using a facile method. The glass-ceramic samples are synthesized with heat treating the parent glass at appropriate temperatures, where different calcium phosphate crystalline phases are grown in the parent glass samples during the heat treatment. The amounts of elements a...

The purpose of this study was the histomorphologic analysis of the efficacy of bioactive glass particles with a narrow size range (Biogran) in the periodontal healing of 2-wall intrabony defects in monkeys. The 2-wall defects were made in the mesial area of the left and right second premolars of four monkeys, filled with gutta-percha and, after 15 days, they were debrided and either naturally f...

In this study, the fabrication and properties of a synthetic keratoprosthesis skirt for use in osteo-odonto-keratoprosthesis (OOKP) surgery are discussed. In the search for a new material concept, bioactive glass and polymethyl methacrylate (PMMA)-based composites were prepared. Three different bioactive glasses (i.e. 45S5, S53P4 and 1-98) and one slowly resorbing glass, FL107, with two differe...

Biointerface design that targets osteogenesis is a growing area of research with significant implications in biomedicine. Materials known to either support or stimulate osteogenesis are composed of a biomimetic ceramic material, such as bioactive glass. Bioactive glass is osteoproductive, and the potential for osteoproductivity can be enhanced by the addition of proteins or other additives desi...

Traditionally, bioactive glasses have been used to fill and restore bone defects. More recently, this category of biomaterials has become an emerging research field for bone tissue engineering applications. Here, we review and discuss current knowledge on porous bone tissue engineering scaffolds on the basis of melt-derived bioactive silicate glass compositions and relevant composite structures...

SiO(2)-CaO-P(2)O(5) ternary bioactive glass ceramic (BGC) nanoparticles with different compositions were prepared via a three-step sol-gel method. Polyethylene glycol was selected to be used as the surfactant to improve the dispersion of the nanoparticles. The morphology and composition of these BGC nanoparticles were observed by ESEM and EDX. All the BGC particles obtained in this method were ...