نتایج جستجو برای: biomarker screening

تعداد نتایج: 282581  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2003
Katherine R Kozak Malaika W Amneus Suzanne M Pusey Feng Su Mui N Luong Sam A Luong Srinivasa T Reddy Robin Farias-Eisner

One hundred eighty-four serum samples from patients with ovarian cancer (n = 109), patients with benign tumors (n = 19), and healthy donors (n = 56) were analyzed on strong anion-exchange surfaces using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry technology. Univariate and multivariate statistical analyses applied to protein-profiling data obtained from 140 tra...

2014
Anthony Dorling Irene Rebollo-Mesa Rachel Hilton Janet L Peacock Robert Vaughan Leanne Gardner Guilherme Danzi Richard Baker Brendan Clark Raj C Thuraisingham Matthew Buckland Michael Picton Susan Martin Richard Borrows David Briggs Robert Horne Paul McCrone Joanna Kelly Caroline Murphy

BACKGROUND Renal transplantation is the best treatment for kidney failure, in terms of length and quality of life and cost-effectiveness. However, most transplants fail after 10 to 12 years, consigning patients back onto dialysis. Damage by the immune system accounts for approximately 50% of failing transplants and it is possible to identify patients at risk by screening for the presence of ant...

2010
James A. de Lemos

Despite great enthusiasm for biomarkers as tools to enhance risk prediction and to lead the way in a transformation towards personalized cardiovascular medicine, progress in the biomarker field has been painstakingly slow, particularly in the area of population screening. Some individual biomarkers such as C-reactive protein (CRP) have demonstrated consistent associations with incident cardiova...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008
Gaëlle A V Boulet Caroline A J Horvath Sarah Berghmans Johannes Bogers

Cervical cytology screening has reduced cervical cancer morbidity and mortality but shows important shortcomings in terms of sensitivity and specificity. Infection with distinct types of human papillomavirus (HPV) is the primary etiologic factor in cervical carcinogenesis. This causal relationship has been exploited for the development of molecular technologies for viral detection to overcome l...

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