نتایج جستجو برای: biomarker validation

تعداد نتایج: 227799  

Journal: :Statistical Methods in Medical Research 2017

Journal: :Journal of Statistical Planning and Inference 2008

2017
Henry A. Adeola Jonathan M. Blackburn Timothy R. Rebbeck Luiz F. Zerbini

Various biomarkers have emerged via high throughput omics-based approaches for use in diagnosis, treatment, and monitoring of prostate cancer. Many of these have yet to be demonstrated as having value in routine clinical practice. Moreover, there is a dearth of information on validation of these emerging prostate biomarkers within African cohorts, despite the huge burden and aggressiveness of p...

2015
Marta del Campo Wesley Jongbloed Harry A. M. Twaalfhoven Robert Veerhuis Marinus A. Blankenstein Charlotte E. Teunissen

Different neurodegenerative disorders, such as Alzheimer's disease (AD) and frontotemporal dementia (FTD), lead to dementia syndromes. Dementia will pose a huge impact on society and thus it is essential to develop novel tools that are able to detect the earliest, most sensitive, discriminative, and dynamic biomarkers for each of the disorders. To date, the most common assays used in large-scal...

Journal: :The British journal of nutrition 2001
A Kroke K Klipstein-Grobusch K Hoffmann I Terbeck H Boeing A Helander

Under-reporting of alcohol intake has been frequently reported. However, due to the lack of an objective reference method, e.g. a biomarker, information about the extent of under-reporting of alcohol intake obtained with dietary assessment instruments is not available. The objective of this study was to compare reported alcohol intake data derived from a 24 h recall with a biomarker of recent a...

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