Editor—A review in the BJA in 2010 suggested that advantages of using ultrasound guidance in regional anaesthesia included direct visualization of structures and local spread, detection of anatomical variants, reduction in local anaesthetic volume, painless blocks, and improved block performance and patient satisfaction. We feel that the following case demonstrates an additional benefit of ultr...

TOPIC: Critical Care TYPE: Medical Student/Resident Case Reports INTRODUCTION: Central venous catheters (CVCs) are used in decompensating patients for central monitoring, rapid fluid resuscitation, drug administration, and hemodialysis (1,2). Risks from CVC placement numerous can include vascular, cardiac pulmonary complications (1). CASE PRESENTATION: A 36-year-old male with past medical histo...

formation of large informatic databases, or clinical quality registries, linking preoperative and intraoperative clinical data, imaging, genomics, and cancer and drug prescription databases. From a clinical perspective, we forsee patients undergoing the same operation receiving a different anaesthetic depending on their outcome risk. Taking knee arthroplasty as an example, patients deemed at lo...

if we make a cursory look at the present trend of journals in the  discipline  of  anesthesia  and  articles  that  they publish, we are overwhelmed both by their number and the highly elegant and innovative works that they publish. in the beginning of the 20th century i.e., 1922, the first journal of anesthesia, anesthesia & analgesia (a & a) was launched and published by the international ane...

Following major non-cardiac surgery, large numbers of patients have biochemical evidence perioperative myocardial injury (PMI) associated with increased and long-term morbidity mortality.1 Recent work suggests inflammation is a driver PMI.2 Our research group previously demonstrated right (but not left) ventricular dysfunction in undergoing lung resection hypothesised that an inflammatory to th...

March 22, 1994 A wealthy eccentric places two envelopes in front of you. She tells you that both envelopes contain money, and that one contains twice as much as the other, but she does not tell you which is which. You are allowed to choose one envelope, and to keep all the money you find inside. This may seem innocuous, but it generates an apparent paradox. Say that you choose envelope 1, and i...

We have found that when copper, zinc or cobalt is bound to a suitable ligand, the appropriate complex exhibited a significant anti-HSV effect (Varadinova et al., 1993; 1996). Recently published data by Sagripanti et al. (1997) also show that the inhibition of HSV by copper was enhanced by reducing agents and that mechanism of the inactivation is similar as for copper-mediated DNA damage (Aruoma...

references: 1. miller rd. miller’s anesthesia. 7th ed. philadelphia: churchill livingstone 2010 2758-9. 2. macintyre pe, schug sa, scott da, visser ej, walker sm. apm:se working group of the australian and new zealand college of anaesthetists and faculty of pain medicine. acute pain management: scientific evidence. 3rd ed. melbourne: anzca & fpm 2010 9-12. 3. buvanendran a. chronic postsurgical...