Chronic myelogenous leukemia (CML) evolves from a chronic phase characterized by the Philadelphia chromosome as the sole genetic abnormality into blast crisis, which is often associated with additional chromosomal and molecular secondary changes. Although the pathogenic effects of most CML blast crisis secondary changes are still poorly understood, ample evidence suggests that the phenotype of ...

Chilling reduces the number of Campylobacter on pork meat. The humidity during chilling is expected to have an influence on the reduction of Campylobacter. In this study, bellies taken from carcasses before chilling have been inoculated either with a mixture of C. jejuni isolates or C.coli isolates and chilled with blast chilling or conventional chilling combined with two levels of relative hum...

BACKGROUND The study evaluates a group of Military Service Members specialized in blast explosive training called "Breachers" who are routinely exposed to multiple low-level blasts while teaching breaching at the U.S. Marine Corps in Quantico Virginia. The objective of this study was to determine if there are any acute or long-term auditory changes due to repeated low-level blast exposures used...

The main focus of this study was the effect of a full blast wave on lightweight nonstructural components, such as window glazing. Both the positive and negative phases of the blast pulse were considered. Previously, structural analysis models considered only the positive phase of the blast load. The structural response is defined by the peak positive and negative values of the pressure, the dur...

Chronic myelogenous leukemia (CML) evolves from a chronic phase characterized by the Philadelphia chromosome as the sole genetic abnormality into blast crisis, which is often associated with additional chromosomal and molecular secondary changes. Although the pathogenic effects of most CML blast crisis secondary changes are still poorly understood, ample evidence suggests that the phenotype of ...

Repeated exposure to low-level blast is a characteristic of a few select occupations and there is concern that such occupational exposures present risk for traumatic brain injury. These occupations include specialized military and law enforcement units that employ controlled detonation of explosive charges for the purpose of tactical entry into secured structures. The concern for negative effec...

In cultures of spleen cells from normal mice, recombinant human granulocyte colony-stimulating factor (G-CSF) supported the formation of multipotential blast cell colonies. Serial replating of the blast cell colonies in the presence of G-CSF, however, failed to demonstrate any direct effect of G-CSF on murine multipotential progenitors. We therefore examined the effects of G-CSF in combination ...

As the gathering of information on the prevalence of blast-induced traumatic brain injuries (bTBI) continues, there is a need for the development and validation of a physical model (headform) reproducing the mechanical response of the human head to the direct loading from a blast wave. The chain of events leading to an injuries following direct exposure to a blast wave is very complex and its f...