INTRODUCTION: Viral and bacterial transmission are possible adverse outcomes of utilizing banked tissues for transplantation. Concerns that current freezing and storage practices may not be adequate to inactivate retroviruses were substantiated by recent animal model studies. These studies documented viral transmission from retrovirus-infected, transplanted allogeneic cortical and cancellous bo...

Bone grafting has increasingly been used in surgical procedures for enhanced bone augmentation. Tooth-derived graft material received considerable attention due to its chemical composition and autogenous source that can improve tissue healing. The main aim of this study was provide a short comprehensive review on the composition, morphological aspects, clinical outcomes using tooth-derived matr...

OBJECTIVES The aim of this in vitro study was to compare the efficacy of Amorphous Calcium Phosphate (ACP)-containing orthodontic composite and resin-modified glass ionomer cement (RMGIC) on enamel demineralization adjacent to orthodontic brackets evaluated by a new laser fluorescence device. METHODS Sixty extracted maxillary premolars were used in the present study. Twenty orthodontic bracke...

This study aimed to explore the effect of fluoridated toothpastes on biofilm architecture and enamel demineralization in an in vitro biofilm model. Streptococcus mutans was grown on enamel and treated with slurries of commercial toothpastes, containing SnF2 or NaF. Water and chlorhexidine were used as negative and positive controls, respectively. The developed biofilms were imaged and enamel de...

Dental caries is a multifactorial disease caused by the interaction of dietary sugars, dental biofilm, and tissue host. It results from repeated cycles demineralization remineralization at interface biofilm tooth surface. Demineralization process removing mineral ions hydroxyapatite crystals in hard tissues, such as enamel, which can lead to if left unchecked. The reverse lost that occur during...

Several reports have shown the deleterious effects of weightlessness on astronauts. Among the pathological conditions recorded, those involving the skeleton are dramatic, characterised by a decrease of bone mass and by bone demineralization, eventually leading to osteoporosis. This is consistent with the notion that mechanical loading is critical for the maintenance of a correct bone mass, sinc...

BACKGROUND The acid-ash hypothesis posits that increased excretion of "acidic" ions derived from the diet, such as phosphate, contributes to net acidic ion excretion, urine calcium excretion, demineralization of bone, and osteoporosis. The public is advised by various media to follow an alkaline diet to lower their acidic ion intakes. The objectives of this meta-analysis were to quantify the co...

The present studies show for the first time that demineralized bone re-calcifies rapidly when incubated at 37 °C in rat serum: re-calcification can be demonstrated by Alizarin Red and von Kossa stains, by depletion of serum calcium, and by uptake of calcium and phosphate by bone matrix. Re-calcification is specific for the type I collagen matrix structures that were calcified in the original bo...

INTRODUCTION Enamel demineralization is an undesirable side effect of orthodontic treatment with fixed appliances. The purpose of this in-vitro study was to evaluate the efficacy of applying a light-cured filled sealant onto the buccal tooth surfaces to prevent demineralization. METHODS Fifty extracted human third molars were allocated to 1 of 5 groups: (1) enamel surface untreated (control);...