Mutations in the HFE gene may be associated with increased tissue iron stores reflected in an elevated serum ferritin. With homozygous mutation C282Y, the increase in serum ferritin may be associated with tissue damage in the liver, pancreas, and pituitary and with a reduced bone mineral density. With heterozygous mutation C282Y, the degree of iron retention is less but information relating to ...

To investigate associations of lifestyle factors with bone mineral density among young men in Japan, we measured bone mineral density of the second metacarpal bone in 143 male university students, aged 18-22 years, by the computed X-ray densitometry. The subjects completed a lifestyle questionnaire including a quantitative food frequency questionnaire. Their mean+/-standard deviation of bone mi...

Introduction: Various therapeutic options such as Calcitonin are suggested for patients with low bone density. However, the efficacy remains uncertain in all patients. C-telopeptide of type I collagen (CTx) is the authentic bone marker which is recently used to assess the bone turnover. This study aimed at revealing the therapeutic effects of Calcitonin on osteopenic women via ...

BACKGROUND Metabolic bone disease has long been associated with cholestatic disorders. However, data in noncholestatic cirrhosis are relatively scant. AIMS To determine prevalence and severity of low bone mineral density in noncholestatic cirrhosis and to investigate whether age, gender, etiology, severity of underlying liver disease, and/or laboratory tests are predictive of the diagnosis. ...

OBJECTIVES A longitudinal study was conducted to investigate the relationships of the change in radius bone mineral density for seven years with lifestyle, body measurement data and laboratory data. METHODS The subjects of this study were 191 female employees working in an LSI manufacturing factory in Japan. Bone mineral density was measured on the radius of their nondominant side using DXA (...

BACKGROUND Persons with unilateral, lower-extremity amputation sometimes develop osteoarthritis in the intact limb. The purpose of this study was to investigate gait mechanics and bone mineral density in unilateral, trans-tibial amputees to test the hypotheses that the intact limb knee and hip will have larger frontal plane net joint moments and bone mineral density than the prosthetic side and...

BACKGROUND/AIMS Calcium and vitamin D malabsorption in coeliac disease predispose to skeletal demineralisation. This study aimed to determine bone mineral density in patients studied in the first year after diagnosis of coeliac disease, and to detect changes in bone mineral density over the subsequent year. METHODS Lumbar spine and femoral neck bone mineral density was measured in 21 adults w...

OBJECTIVE The purpose of this study was to analyze the relationship between martial arts practice (judo, karate and kung-fu) and bone mineral density in adolescents. METHODS The study was composed of 138 (48 martial arts practitioners and 90 non-practitioners) adolescents of both sexes, with an average age of 12.6 years. Bone mineral density was measured using Dual-Energy X-ray Absorptiometry...

background: revealing data on the role of vitamin d and calcium supplementation in bone health has led some to suggest that vitamin d and calcium treatment could also play a role in protecting bone against microgravity-induced mineral loss. objectives: the aim of the present study was to investigate the effects of vitamin d and calcium administration on microscopic and densitometric changes of ...

background: the aim was to investigate the relationships among lean mass (lm), fat mass (fm), and bone mineral density (bmd) in women stratified by body mass index (bmi) (bmi – normal-weight, overweight, obese) and to determine threshold at which body fat assumes negative relationship with bmd. methods: this was a cross-sectional study in 471 healthy caucasian women, aged 18-67 years. bmd, lm, ...