OBJECTIVE This study assessed histologically the effect of laser photobiomodulation (LPBM) on the repair of surgical defects created in the femurs of Wistar rats treated or not treated with bone morphogenic proteins (BMPs) and organic bovine bone graft. BACKGROUND DATA This paper is part of an ongoing series of works in which biomaterials are used in association with LPBM. Several previous re...

Hypocalcemia and hypophosphatemia are common complications after parathyroidectomy (PTX). Sudden removal of high circulating levels of parathyroid hormone (PTH) causes decreased osteoclastic resorption resulting in a decreased bone remodeling space. These phenomena are likely due to an increased influx of calcium and phosphorus into bone. However, there are currently no data to support this hyp...

OBJECTIVE Evaluate the effect of raw bovine cortical bone (CB) (medullary bone cross-sectioned) and marrow or epiphyseal 'spongy' bone (SB) as chew items to reduce dental calculus in adult dogs. METHODS Eight 3-year-old Beagle dogs were observed in two study periods. In the first study, the dogs each received a piece of bovine femur CB (122 ± 17 g) daily and in the second study, a piece of bo...

We have isolated and sequenced cDNAs encoding human and bovine bone Gla protein (BGP, osteocalcin), a low molecular weight polypeptide specific to bone. A XZAP cDNA library constructed from human osteosarcoma poly A RNA was screened with a unique ^P-labeled oligonucleotide probe (27 mer) encoding the nine N-terminal amino acids of the human BGP precursor protein (1). Below is shown the nucleoti...

BACKGROUND Increasing sinus pneumatization and the accompanying alveolar bone resorption complicate dental implant placement. This problem can be overcome today by raising the maxillary sinus floor with graft materials. Bisphosphonates are commonly used to accelerate the recovery of the graft materials and to prevent resorption. OBJECTIVES The purpose of this study is to investigate whether s...

Tissue engineering is now contributing to new developments in several clinical fields, and mesenchymal stem cells derived from adipose tissue (hASCs) may provide a novel opportunity to replace, repair and promote the regeneration of diseased or damaged musculoskeletal tissue. Our interest was to characterize and differentiate hASCs isolated from twenty-three donors. Proliferation, CFU-F, cytofl...

A bone-inductive protein has been purified from bovine bone and designated as osteogenic protein (OP). The purified OP induces new bone at less than 5 ng with half-maximal bone differentiation activity at about 20 ng/25 mg of matrix implant in a subcutaneous bone induction assay. The purified osteogenic protein is composed of disulfide-linked dimers that migrate on sodium dodecyl sulfate gels a...

The propagation of both fast and slow longitudinal waves in bovine cancellous bone in vitro was experimentally examined by the pulse transmission technique in relation to the bone density. Experimental results show that the propagation speed and the amplitude of the fast wave increase greatly with the bone density and those of the slow wave decrease reversely with the bone density.

We present the use of deproteinized bovine bone mineral and a non-crosslinked collagen membrane for reconstruction significant alveolar defect in this clinical case report,. The patient had extensive loss anterior maxillary region, posing challenge implant placement. Therefore, ridge preservation was performed following tooth extraction, resulting horizontal regeneration. Two implants were subs...