نتایج جستجو برای: bradyzoite

تعداد نتایج: 163  

Journal: :Journal of clinical pathology 1995
Y W Zhang A Fraser A H Balfour T G Wreghitt J J Gray J E Smith

AIMS To obtain quantitative data on the human serological response to Toxoplasma gondii tachyzoite and bradyzoite antigens. METHODS Serum samples from 30 patients who had positive antibody titres against T gondii and from 14 who were seronegative, together with sequential serum samples from four infected individuals, were screened by FAST-ELISA. RESULTS Serum samples from the 30 seropositiv...

Journal: :Antimicrobial agents and chemotherapy 2005
Sabrina Sonda Giusy Sala Riccardo Ghidoni Andrew Hemphill Jean Pieters

The apicomplexan parasite Toxoplasma gondii is a leading opportunistic pathogen associated with AIDS and congenital birth defects. Due to the need for identifying new parasite-specific treatments, the possibility of targeting sphingolipid biosynthesis in the parasite was investigated. Aureobasidin A, an inhibitor of the enzyme synthesizing the sphingolipid inositol phosphorylceramide, which is ...

Journal: :Infection and immunity 2004
Nathalie Vonlaufen Nicole Guetg Arunasalam Naguleswaran Norbert Müller Camilla Björkman Gereon Schares Daniela von Blumroeder John Ellis Andrew Hemphill

We report on an optimized method for the in vitro culture of tissue cyst-forming Neospora caninum bradyzoites in Vero cells and the separation of viable parasites from host cells. Treatment of tachyzoite-infected Vero cell cultures with 17 microM sodium nitroprusside for 8 days severely scaled down parasite proliferation, led to reduced expression of tachyzoite surface antigens, and induced the...

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