Background: The therapeutic potential of honey is related to antioxidant activity against reactive oxygen species because it contains compounds such as polyphenols; therefore, we evaluated the potential protective effect of honey on subacute toxicity of ACR by histopathologic study on tissue lesions in rat. Methods: In Ferdowsi University of Mashhad, Mashhad, Iran, 2016, male Wistar rats were ...

abstract pollution is a world problem with serious consequences. heavy metals are an important group of these contaminants and enter aquatic ecosystems from anthropogenic and natural sources and animal health and systems are affected. in this study, the effect of lead exposure (3 mg/l concentration, 30 days) on activity of tissue enzymes, including acetyl cholinesterase, alanine aminotransferas...

Background and objectives: Increased oxidative stress and altered antioxidant levels play an essential role in the pathogenesis of diabetes mellitus. Menopause is associated with increased food intake, weight gain, metabolic disorders, and increased level of inflammatory and oxidative stress factors. This study evaluated effects of oleuropein extract on brain tissue and serum oxidative status i...

Despite being a critical molecule in the brain, mass spectrometry imaging (MSI) of cholesterol has been under-reported compared to other lipids due difficulty ionizing sterol molecule. In present work, we have employed an on-tissue enzyme-assisted derivatization strategy improve detection brain tissue sections. We report distribution and levels across specific structures mouse model Niemann-Pic...

BACKGROUND:Uncontrolled application of diazinon (DZN)can cause environmental contamination and adverse healtheffects on humans or animals. OBJECTIVES:This study aimed toinvestigate the toxic effects and the level of DZN in serum andtissues of rabbits following a sub acute dermal exposure totoxicant. METHODS:Different doses of DZN were applied dailyto New Zealand rabbits through the ear skin in ...

Normal Pressure hydrocephalus (NPH) is characterized by gait apraxia, urinary incontinence, and dementia. Mixed connective tissue disease (MCTD) is an autoimmune connective tissue disease that has never been reported to cause NPH. Our patient was a 67-year man with a one-year history of gradual worsening gait and balance, urinary urgency with urge incontinence and decreased short-term memory. P...

Background: Extensive research has been focused on radiation induced brain injury. Animal and human studies have shown that flavonoids have remarkable toxicological profiles. This study aims to investigate the neuroprotective effects of hesperidin in an experimental radiation induced brain injury. Materials and Methods: 32 adult male Wistar-Albino rats were randomly divided into 4 groups (contr...

Background: Our purpose was to investigate propolis and its component caffeic acid phenethyl ester (CAPE) for their antioxidant effects on the brain tissue of rats exposed to ionizing radiation (IR). Materials and Methods: Fifty-four male albino Sprague-Dawley rats, divided into six groups, were designed as normal control group, cranial irradiation of 5 Gray alone, irradiation plus CAPE, irradi...

This paper highlights the various factors that contribute to scattering coefficient variations within human brain tissues and theoretical penetration depth. These are critical parameters for biomedical applications neuroscience research. Brain tissue’s complex nature, experimental technique variability, tissue composition structure, type, sample preparation, temperature all potentially impact o...