Introduction: Accelerated Partial Breast Irradiation (APBI) is an effective treatment for breast carcinomas because of its limited number of fractions. Strut-adjusted volume implant (SAVI) is a HDR brachytherapy applicator to deliver the prescription dose with good PTV coverage and acceptable dose to skin, chest wall and organ at risks. Acceptable clinical outcomes depend on a...

PURPOSE This technical note quantifies the dose and image quality performance of a clinically available organ-dose-based tube current modulation (ODM) technique, using experimental and simulation phantom studies. The investigated ODM implementation reduces the tube current for the anterior source positions, without increasing current for posterior positions, although such an approach was also e...

AIM OF THE STUDY Accurate skin dose assessment is necessary during breast radiotherapy to assure that the skin dose is below the tolerance level and is sufficient to prevent tumour recurrence. The aim of the current study is to measure the skin dose and to evaluate the geometrical/anatomical parameters that affect it. MATERIAL AND METHODS Forty patients were simulated by TIGRT treatment plann...

BACKGROUND X-ray mammography is one of the general methods for early detection of breast cancer. Since glandular tissue in the breast is sensitive to radiation and it increases the risk of cancer, the given dose to the patient is very important in mammography. OBJECTIVES The aim of this study was to determine the average absorbed dose of X-ray radiation in the glandular tissue of the breast d...

Because modern digital detectors can be tuned to be more efficient than screen-film systems, they automatically lower the radiation dose to the patient while maintaining the image quality radiologists crave. Photon-counting, the method used in Sectra's detector, for example, minimizes patient exposure to radiation. In a 2006 analysis, the British National Health Service Breast Screening Program...

Mammography is an x-ray examination of the breast usually done for breast cancer screening and accompanied by further development of both invasive and non-invasive radiological technique used for establishing the diagnosis of palpable and non palpable lesions [1,2]. The major projection for x-ray mammography includes cranio-caudal and mediolateral obliques view. There are two types of patients ...

Purpose: The purpose of the current work was experimental investigations of the mean breast dose and volume dose distributions with and without adaptive filtration. Adaptive filtration of the x-ray beam is used in dedicated breast CT to reduce dynamic range requirements on the detector, and to improve image quality. The adaptive filter has a predetermined shape, it is placed after the x-ray sou...

BACKGROUND This study compared three methods of estimating the daily dose of fluoxetine to nursing infants and the relationship between these estimates and infant serum concentrations. METHODS Breast milk and infant serum concentrations of fluoxetine and norfluoxetine were obtained from 10 nursing mother-infant pairs. Quantification of daily infant dose was determined by three methods: 1) col...

PURPOSE Noninvasive image-guided breast brachytherapy delivers conformal HDR (192)Ir brachytherapy treatments with the breast compressed, and treated in the cranial-caudal and medial-lateral directions. This technique subjects breast tissue to extreme deformations not observed for other disease sites. Given that, commercially-available software for deformable image registration cannot accuratel...

BACKGROUND Evidence shows ionizing radiation can cause lung cancer, but few studies have quantified risk in relation to radiation dose. PURPOSE This study evaluated the long-term risk of lung cancer among women treated with radiation for breast cancer. METHODS In this case-referent study, the Connecticut Tumor Registry was used to identify women diagnosed with histologically confirmed invas...