Phyllodes tumors are rare fibroepithelial neoplasms of the breast, classified as benign, borderline, or malignant based on histological features. Osseous metaplasia, characterized by presence bone formation within tumor, is an uncommon finding. This case report highlights rarity osseous metaplasia in a benign phyllodes tumor. A 23-year-old female presented with gradually enlarging lump left bre...

conclusion the possibility of malignancy is strongly indicated when additional nme lesions show linear or segmental enhancement on preoperative 3t dce-mri in patients with recently diagnosed breast cancer. results on histopathologic analysis of the 88 nme lesions, 73 (83%) were malignant and 15 (17%) were benign. lesion size did not differ significantly between malignant and benign lesions (p =...

The difficulties of timely diagnosis primary multiple synchronous breast cancer with histological heterogeneity tumors are demonstrated by a clinical example. Taking into account the fact that continues to lead among all oncological pathology and accounts for 11.8% malignant neoplasms, diagnostic algorithms stage should be personalized. presented case demonstrates multidisciplinary errors commi...

Malignant neoplasms diagnosed histologically in the state of Sabah during the period November 1983 to October 1988 were analysed to determine the distribution of malignant neoplasms according to site, age, sex and major ethnic groups. The five commonest malignant neoplasms in males were carcinomas of the nasopharynx, stomach, skin, lung and liver. In females the five commonest malignant neoplas...

Mutations in the chromatin remodeling gene ARID1A have recently been identified in the majority of ovarian clear cell carcinomas (OCCCs). To determine the prevalence of mutations in other tumor types, we evaluated 759 malignant neoplasms including those of the pancreas, breast, colon, stomach, lung, prostate, brain, and blood (leukemias). We identified truncating mutations in 6% of the neoplasm...

BACKGROUND Lymphatic mapping and sentinel lymph node biopsy is an established technique for the staging and treatment of melanoma. The success of lymphatic mapping in this realm has broadened its application to other solid neoplasms. This update reviews the status of sentinel lymph node biopsy in its most widely cited applications. METHODS Seminal manuscripts on lymphatic mapping in melanoma,...

The transcription factor LMO2 is involved in vascular and hematopoietic development and hematolymphoid neoplasia. We have demonstrated that LMO2 is expressed nearly ubiquitously in native and neoplastic vasculature, including lymphatics. LMO2 reactivity is otherwise virtually absent in nonhematolymphoid tissues except in breast myoepithelium, prostatic basal cells, and secretory phase endometri...

Out of all the different types of neoplasms affecting the stomach, gastric carcinomas with Osteoclast-like Giant Cells (OGC) is one of the most uncommon. Although OGC are typically found in osseous neoplasms and tumors of the tendon sheath, few cases of extra-skeletal neoplasms with OGC have been documented. These typically involve organs such as the pancreas, gall-bladder, kidney, and breast. ...

Metastatic adenocarcinoma to the breast from an extramammary site is extremely rare. In the literature, the most current estimate is that extramammary metastases account for only 0.43% of all breast malignancies and that, of these extramammary sites, colon cancer metastases form a very small subset. Most commonly seen metastasis in breast is from a contralateral breast carcinoma, followed by me...