BACKGROUND The goal of this study was to develop and validate the overall benefit of analgesic score (OBAS), which assesses pain intensity and the opioid-related adverse effects. METHODS The score was developed and validated in four trials (n=1470 patients). Data from randomized trial I were used to develop the OBAS (factor analysis). Data from randomized trial II were used to compare the res...

OBJECTIVE We examined whether tailored activity pacing intervention was more effective at reducing pain and fatigue than general activity pacing intervention. METHOD Adults with knee or hip osteoarthritis (N = 32) stratified by age and gender were randomized to receive either tailored or general pacing intervention. Participants wore an accelerometer for 5 days that measured physical activity...

PURPOSE To assess the efficacy of pregabalin by showing differences in the neuronal activities of fibromyalgia (FM) patients before and after longitudinal treatment using functional magnetic resonance imaging (fMRI). MATERIALS AND METHODS In total, 21 female patients with FM and 11 age- and gender-matched healthy controls participated. FM patients underwent fMRI at baseline and following phar...

BACKGROUND While there are reports on vision-related quality of life in patients with vision impairment caused by both ophthalmic and brain diseases, little is known about mental distress. In fact, mental distress after cerebral visual injury has been widely ignored. METHODS Mental health symptoms were assessed in 122 participants with visual field defects after brain damage (72 male, mean ag...

Visual disorders are associated with a substantial economic and personal burden (Rein, 2013). The recent paper by Gall et al. (2015) examined the influence of visual disorder on one aspect of this burden, mental health. Their study involved 122 participants (mean age= 58.1± 15.6 years, 72 males, 61% either married or in a relationship) who had visual field defects associated with cerebral visua...

BACKGROUND Using self-report questionnaires of key fibromyalgia symptom domains (pain, fatigue, sleep disturbance, function, stiffness, dyscognition, depression, and anxiety), we previously identified four unique symptom clusters. The purpose of this study was to examine the stability of fibromyalgia symptom clusters between baseline and 2-year follow-up. METHODS Women with a diagnosis of fib...