BACKGROUND In India where the prevalence of extended spectrum beta lactamase (ESBL) producing organisms among gram negative organisms is 60-70% and Ertapenem was unavailable at the beginning of this study, exclusive use of Group 2 Carbapenems (Imipenem and Meropenem) for treatment raises issues of cost and development of resistance. Therefore the role of non-Carbapenem alternatives, chiefly Bet...

in the promoter –attenuator region of the chromoso-mal ampC gene were also studied by PCR and sequencing. 3 Broad-spectrum cephalosporin-resistant E. coli strains were detected in five of the 75 faecal samples analysed (6.6%, four dogs and one cat). Four of the five strains, obtained from four unrelated dogs, gave positive ESBL screening test results and were resistant to cefotaxime and/or ceft...

Of 72 blood isolates of Enterobacter spp. collected over an 8-year period, 50% (36 of 72) were derepressed or partially derepressed AmpC mutants. The extended-spectrum -lactamase (ESBL) production rate was 43% (31 of 72 isolates), and 67.3% (31 of 46) of extended-spectrum cephalosporin-resistant strains produced ESBLs. Thus, a confirmatory test for ESBL production is necessary for extended-spec...

Escherichia coli and Klebsiella spp., followed by Serratia spp. and Enterobacter spp., are the most frequent Gram-negative pathogens isolated from bovine clinical mastitis (8). The incidence of mastitis due to such bacteria has increased in recent years (7). Klebsiella is usually referred as particularly aggressive and prone to cause severe clinical mastitis, which responds poorly to treatment ...

This study evaluated the added value of selective preenrichment for the detection of rectal carriage of extended-spectrum-beta-lactamase-producing Enterobacteriaceae (ESBL-E). ESBL-E rectal carriage was identified in 4.8% of hospitalized patients, and 25.9% of ESBL-E rectal carriers were identified with selective preenrichment only.

extended-spectrum β-lactamase (esbl)-producing enterobacteria has become a considerable global concern because of their potential dissemination in humans, in domestic animals, wildlife and the environment. the present study aimed to explore the esbl producing  enterobacteria in aquatic sources of bangladesh as the water may be the potential source of dissemination of this alarming antimicrobial...

BACKGROUND/AIMS We examined the prevalence of extended-spectrum β-lactamase (ESBL) production and the impact of ESBL on clinical outcomes in cancer patients with Enterobacter spp. bacteremia. METHODS Using prospective cohort data on Enterobacter bacteremia obtained between January 2005 and November 2008 from a tertiary care center, the prevalence and clinical impact of ESBL production were ev...

Extended-spectrum beta-lactamases (ESBLs) are enzymes produced in some gram-negative bacilli that mediate resistance to extended-spectrum cephalosporins and aztreonam. They are most common in Klebsiella spp. and Escherichia coli but are present in a variety of Enterobacteriaceae. Resistance mediated by these enzymes can be difficult to detect depending on the antimicrobial agents tested. AmpC b...

This study was carried out to determine the prevalence of Extended-spectrum -lactamase (ESBL) and their antibiotic resistance patterns from clinical isolates in a university hospital. A total of One hundred and seventy-two isolates of Gram-negative were identified using Standard Laboratory Methods from various clinical specimens. Antibiotics susceptibility test was performed using disc diffusio...