نتایج جستجو برای: bse function
تعداد نتایج: 1215102 فیلتر نتایج به سال:
Rapid BSE tests are widely used diagnostics in veterinary medicine and more than 11 million tests are applied worldwide. The evaluation of new rapid BSE tests and the quality assurance of approved BSE tests pose a challenge owing to the natural scarcity of BSE-infected bovine brainstems and regional variations in prion titer. Transgenic mice expressing bovine prion protein (Tg4092) offer an alt...
BACKGROUND Transmissible Spongiform Encephalopathies (TSEs), including scrapie in sheep, chronic wasting disease (CWD) in cervids, transmissible mink encephalopathy (TME), and bovine spongiform encephalopathy (BSE), are fatal diseases of the nervous system associated with accumulation of misfolded prion protein (PrP(Sc)). Different strains of TSEs exist, associated with different PrP(Sc) confor...
BACKGROUND Various clinical protocols have been developed to aid in the clinical diagnosis of classical bovine spongiform encephalopathy (BSE), which is confirmed by postmortem examinations based on vacuolation and accumulation of disease-associated prion protein (PrPd) in the brain. The present study investigated the occurrence and progression of sixty selected clinical signs and behaviour com...
John Chambers (British Society of Echocardiography) Cardiothoracic Centre, Guy's and St Thomas Hospitals, London Ahmet Fuat (Primary Care Cardiovascular Society) Strat Liddiard (CHD collaborative) Poole PCT Theresa McDonagh (British Heart Failure Society) Cardiology Department, Western Infirmary, Glasgow Mark Monaghan (BSE) Cardiac Department, King's College Hospital, London Petro...
We recently reported the intraspecies transmission of L-type atypical bovine spongiform encephalopathy (BSE). To clarify the peripheral pathogenesis of L-type BSE, we studied prion distribution in nerve and lymphoid tissues obtained from experimentally challenged cattle. As with classical BSE prions, L-type BSE prions accumulated in central and peripheral nerve tissues.
Sheep CH1641-like transmissible spongiform encephalopathy isolates have shown molecular similarities to bovine spongiform encephalopathy (BSE) isolates. We report that the prion protein PrPSc from sheep BSE is extremely resistant to denaturation. This feature, combined with the N-terminal PrPSc cleavage, allowed differentiation of classical scrapie, including CH1641-like, from natural goat BSE ...
BACKGROUND In many of the European countries affected by Bovine Spongiform Encephalopathy (BSE), case clustering patterns have been observed. Most of these patterns have been interpreted in terms of heterogeneities in exposure of cattle to the BSE agent. Here we investigate whether spatial clustering is present in the Dutch BSE case data. RESULTS We have found three spatial case clusters in t...
Breast Self-Examination (BSE) is always thought to be done by most women only. However, men are also susceptible to breast cancer and as such, also needs to perform Breast Self-Examination (BSE). In this study, the awareness, compliance; and confidence of the participants on BSE was done among 496 students, between male and female participants, of different year levels and from different colleg...
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