This paper considers the novel problem of upgrading a legacy network into Software Defined Network (SDN) over multiple stages and saving energy in upgraded network, or hybrid SDN. That is, each stage, at hand is to select replace switches with SDN reroute traffic power off as many unused cables...

INTRODUCTION The objective of this paper is the comparison between two different technologies used for the removal of a uterine myoma, a frequent benign tumor: the standard technology currently used, laparoscopy, and an innovative one, colpoceliotomy. It was considered relevant to evaluate the real and the potential effects of the two technologies implementation and, in addition, the consequenc...

BACKGROUND Rotavirus (RV) infection is the first cause of acute viral gastroenteritis in children under five years of age all over the world; it mainly affects children between six and 24 months of age and can cause serious acute diarrhoea and dehydration. The aim of this study is to perform the budget impact analysis of universal rotavirus vaccination in the Local Health Unit (LHU) 11 Empoli, ...

Fundamental tradeoffs between energy consumption and sustainable quality of services such as throughput and response time are critical in sensor networks because of limited and often irreplaceable battery power. This paper presents a novel energy saving approach, namely route-awareness. This approach provides a wide spectrum of design alternatives even under an extremely low energy budget. Rout...

The energy demand in the enterprise market segment demands a supply format that accommodates all generation and storage options with active participation by end users in demand response. Basically, with today’s high power computing (HPC), a highly reliable, scalable, and cost effective energy solution that will satisfy power demands and improve environmental sustainability will have a broad acc...

OBJECTIVES Although trastuzumab is traditionally used in metastatic breast cancer treatment, studies reported on the efficacy and safety of trastuzumab in adjuvant setting for the treatment of early stage breast cancer in HER2+ tumors. We estimated the cost-effectiveness and budget impact of reimbursing trastuzumab in this indication from a payer's perspective. METHODS We constructed a health...

While the semiconductor roadmap is about to locate in 16nm-FinFET (or Tri-Gate) era, power budget is being entitled major concern to contemporary electronics and future nanometer devices. In this work, a new Power Distribution Network (PDN), referred to as HiPDN, is disclosed for further fine-grain power saving and higher power integrity for supplies in multi-voltage domains. The proposed PDN e...

This study is motivated by the need to increase energy efficiency in existing buildings. Around 33% of the energy used in the world is consumed in the buildings. Identifying and investing in the right energy saving technologies within a given budget helps the adoption of energy efficiency measures in existing buildings. We present a mathematical programming approach to select the right energy e...