Background & Objective: The spread of carbapenem-resistant Pseudomonas aeruginosa is a global concern. Metallo-beta-lactamase (MBL) enzymes cause extensive drug resistance among Gram-negative bacteria. The current study aimed at determining the prevalence of MBL-producing P. aeruginosa in Iran. Methods<...

BACKGROUND Pseudomonas aeruginosa is considered as a major cause of hospital-acquired infections due to its high antibacterial resistance. Biofilm formation is a well-known pathogenic mechanism in P. aeruginosa infections, since sessile bacteria are protected in an extracellular matrix of exopolysaccharide. The expression of polysaccharide synthesis locus (pslA gene) can be important for biofil...

results the most effective agent against the studied isolates was colistin. by cddt, it was found that among 278 imipenem resistant p. aeruginosa strains, 178(64.02%) were mbl producers. the blaimp-1 and blavim-1 genes were detected in 30(16.8%) and 52(29.2%) of p. aeruginosa isolates, respectively. result of 187 imipenem resistance a. baumannii strains showed that 85(45.4%) were mbl producers....

background the major challenge for a burn team is nosocomial infection, which is known to be responsible for over 50% of burn-related deaths. most studies on infection in burn patients focus on burn wound infection, whereas other nosocomial infections among these patients have not been addressed well. this study attempts to determine three types of nosocomial infections: burn wound, urinary tra...

Introduction: Burn infections are a serious obstacle to the patient’s recovery. Infection is estimated account for 75% of burn patient mortality. Widespread and often indiscriminate administration antibiotics lack basic infection control methods major factors in emergence drug-resistant bacteria. Due growing threat antibiotic resistance, interest silver compounds has grown modern medicine. Obje...

background treatment of infectious diseases is becoming more challenging with each passing year. this is especially true for infections caused by pseudomonas aeruginosa, an opportunistic pathogen with the ability to rapidly develop resistance to multiple classes of antibiotics. objectives this study was conducted to determine the prevalence of metallo-β-lactamase (mbl)–producing strains among m...

BACKGROUND Pseudomonas aeruginosa is an opportunistic pathogen with the ability to cause severe nosocomial infections and remains a major problem in burn patients. This organism shows a remarkable antimicrobial resistance and is often resistant to multiple antibiotics. Integron genes as mobile genetic elements are playing an important role in the spread of P. aeruginosa antibiotic resistance. T...

background metallo-beta-lactamase (mbl) producing pseudomonas aeruginosa in the burn patients is a leading cause of morbidity and mortality and remains a serious health concern among the clinicians. objectives the aim of this study was to detect mbl-producing p. aeruginosa in burn patients and determine multidrug-resistant (mdr) strains, and respective resistance patterns. patients and methods ...

conclusions this study represented an increasing rate of mdr p. aeruginosa in burn and wound samples. efflux mexab genes were detected in all mdr and pdr strains. the p. aeruginosa strain isolated from burn cases showed higher drug resistance and pdr resistance was only noted in a burn sample. materials and methods one-hundred and fifty p. aeruginosa were isolated from burn and wound infections...