Two cases are reviewed, both of which developed tumoral calcinosis whilst receiving 1, alpha-hydroxy-cholecalciferol therapy. Tumoral calcinosis is an extreme form of peri-articular calcification, and its occurrence in patients with chronic renal failure is unusual. These peri-articular masses developed around the shoulders in both patients, and the action of 1, alpha-hydroxycholecalciferol as ...

This is a case of a 69-year-old male patient with long-standing iatrogenic hypoparathyroidism after total thyroidectomy. The clinical evaluation revealed mild neurological symptoms and excessive brain calcinosis. Intracranial calcification that affects structures other than the basal ganglia and the cerebellum is a rare manifestation of postoperative hypoparathyroidism. Detection of brain calci...

Tumoral calcinosis is a distinct clinical and histologic entity that is characterized by tumour like periarticular deposits of calcium that are found foremost in regions of hip, shoulder and elbow. The disorder occurs predominantly in otherwise healthy children, adolescents, young adults and is more often multiple than solitary. We report a case of Tumoral calcinosis in a 15 year old male and d...

Tumoral calcinosis is a rare and benign hereditary tumor-like periarticular calcium deposit. It is painless and it is found commonly around large joints such as hip, shoulder and elbow. The condition predominately affects young black African patients with an equal gender ratio. In this report, a case of primary idiopathic localized tumoral calcinosis in a 22-year-old African man and its distinc...

of other benign neoplasias. Calcified cardiac tuberculomas are infrequent and there is usually a history of tuberculosis,5 which was not the case for our patient. Cardiac tophaceous pseudogout and tumoral calcinosis are 2 rare entities associated with chronic kidney disease. However, tumoral calcinosis commonly appears as a dense calcium extension on the mitral ring and/or the aortic arch, with...

Two cases of tumoral calcinosis occurring in patients with chronic renal failure on hemodialysis are described. The aetiology of tumoral calcinosis is described with particular reference to the patients presented. The metastatic calcification occurring in these two cases is most likely related to hyperphosphataemia and secondary hyperparathyroidism possibly aggravated by vitamin D therapy. Trea...

Case report A girl, 14 years of age, was diagnosed as having JDM when she was 4 years old after a few months of increasing lethargy, muscle pain, muscle weakness, and rash. Calcinosis was recognized 18 months after disease onset. During 3 months, clinical manifestations and abnormal laboratory findings were effectively treated with prednisolone. However, generalized calcinosis rapidly progresse...

BACKGROUND. Tumoral calcinosis is a poorly understood phenomenon. It can be described as a syndrome of calcium deposits principally affecting the juxta-articular areas. It is a rare entity that has been poorly understood. Our aim is to highlight a special and unusual case of an 11-year-old with a large, relatively painless lump in her buttock. CLINICAL CASE. An 11-year-old girl of African desce...

OBJECTIVES Our aim was to perform a pilot study to investigate whether iontophoresis of acetic acid, followed by ultrasound, might be a safe and effective treatment for systemic sclerosis (SSc)-related calcinosis. This combination treatment has been used in other calcifying disorders. METHODS Three female patients (ages 51, 62 and 59 yr) were studied. Each underwent treatment nine times over ...

Skin and subcutaneous lesions of 2 cases with natural occurring Cushing’s disease and 1 case with calcinosis circumscripta were compared. Case 1 was typical of osteoma cutis, containing somewhat regularly arranged discrete ossification foci in the mid and deep dermis. Case 2 had layers of “mille feuille”, yellowish to white gritty chalky substances diffusely scattered in the subcutis, seen hist...