PURPOSE To test the hypothesis that a 24-hour recording of intraocular pressure (IOP)-related measurements derived from a contact lens sensor (CLS) correlates to the rate of visual field progression in treated glaucomatous eyes. DESIGN Prospective, cross-sectional study. PARTICIPANTS Forty treated glaucomatous patients with 8 or more 24-2 visual field tests. METHODS Twenty-four-hour recor...

AIMS Atrial overdrive pacing algorithms increase Atrial Pacing Percentage (APP) to reduce Atrial Tachyarrhythmia (AT) recurrences in patients with Brady-Tachy Syndrome (BTS). This study aimed to compare AT burden and APP in BTS patients treated with conventional DDDR pacing, DDD+ overdrive or Closed-Loop Stimulation (CLS). METHODS AND RESULTS One hundred and forty-nine BTS patients were inclu...

OBJECTIVE Autopsy cases show that cortical lesions (CLs) in multiple sclerosis (MS) lack lymphocyte/macrophage influx, blood-brain barrier breakdown, and complement activation. However, some CLs were demonstrated to harbor activated microglia. Here, we assessed the clinical significance of microglia activation in CLs in a large autopsy sample, and we investigated possible interrelationships wit...

We consider the problem of finding a point in the intersection of an affine set with a compact convex set, called a convex linear system (CLS). The conditional gradient method is known to exhibit a sublinear rate of convergence. Exploiting the special structure of (CLS), we prove that the conditional gradient method applied to the equivalent minimization formulation of (CLS), converges to a sol...

Capillary leak syndrome (CLS) commonly occurs in the intensive care setting. CLS is seen in conditions such as septic shock or may result from conditions such as multitrauma and pancreatitis, which result in the systemic inflammatory response syndrome (SIRS). We present two cases in which both patients suffered with CLS, which we believe was caused following administration of granulocyte colony...

RATIONALE Mechanisms of coronary occlusion in ST-elevation acute coronary syndrome are poorly understood. We have previously reported that neutrophil (polymorphonuclear cells [PMNs]) accumulation in culprit lesion site (CLS) thrombus is a predictor of cardiovascular outcomes. OBJECTIVE The goal of this study was to characterize PMN activation at the CLS. We examined the relationships between ...

During chromosome segregation, kinetochores form dynamic connections with spindle microtubules. In vertebrates, these attachments require the activities of a number of outer kinetochore proteins, including CENP-F [1, 2] and the widely conserved microtubule-associated protein CLASP [3]. Here, we investigate the functional relationship between HCP-1/2, two redundant CENP-F-like proteins, and CLAS...

EIn order to reduce formaldehyde emissions, an experimental investigation of lightweight flax shives based particleboards, prepared using two different binders: bio-based lignin (lignosulfonate) and partially epoxy resin (greenpoxy 56), was undertaken. The particleboards (with a target density 500 kg/m³), were elaborated by thermo-compression process 20 wt% binder content. directly valorised as...