Dr. K. Farrington, Renal Unit, Lister Hospital Stevenage, Coreys Mill Lane, Stevenage, Herts SG1 4AB (UK) Dear Sir, Calcium carbonate is the most commonly used phosphate binder in chronic renal failure (CRF). Recently it has been shown that its phosphate-binding capacity is limited at low pH [1]. This study was performed to assess the effect of the proton pump inhibitor omeprazole on the phosph...

BACKGROUND Calcium-based and non-calcium-based phosphate binders have similar efficacy in the treatment of hyperphosphatemia; however, calcium-based binders may be associated with hypercalcemia, vascular calcification, and adynamic bone disease. SCOPE A post hoc analysis was carried out of data from a 16-week, Phase IV study of patients with end-stage renal disease (ESRD) who switched to lant...

Phosphate is central to bone metabolism and we have therefore studied whether parathyroid hormone (PTH) is regulated by dietary phosphate in vivo. Weanling rats were fed diets with different phosphate contents for 3 wk: low phosphate (0.02%), normal calcium (0.6%), normal phosphate (0.3%), and calcium (0.6%); high phosphate (1.2%), high calcium (1.2%). The low phosphate diet led to hypophosphat...

introduction: this in vitro study measured and compared ph and phosphate and calcium ions release of a new endodontic material (cem cement), mineral trioxide aggregate (mta), and portland cement (pc) using uv-visible technique, atomic absorption spectrophotometry methods, and ph meter, respectively. materials and methods: each material was placed in a plastic tube (n=10) and immersed in a glass...

background: in spermatogenesis, spermatogonial cells differentiate to the haploid gametes. it has been shown that spermatogenesis can be done at in vitro condition. in vitro spermatogenesis may provide an open window to treat male infertility. objective: the aim of this study was to evaluate the effects of a novel scaffold containing human serum albumin (hsa)/tri calcium phosphate nanoparticles...

A simple, sensitive and accurate method for spectrophotometric determination of Dalacinphosphatehas been established. The method is based on the reduction of atomic absorptioncalcium ion by phosphate. Because, there is a phosphate mole in every Dalacin mole structureand with measurement of phosphate, Dalacin is beyond measurement too. Therefore, the reactionbetween acidic hydrolysis products of...

Spontaneous calcification of a membrane made of native collagen has been investigated. The method permits independent variation of calcium and phosphate concentrations. With increasing phosphate concentration the precipitation calcium-phosphate on the collagen occurs at a conspicuously lower calcium concentration as with a number of other membranes.

Cytotoxicity of Calcium Phosphate Crystals and Human-Derived Nanoparticles: An Overlooked Link To the Editor: In a recent communication, Ewence et al reported that calcium phosphate crystals induced cell death in human aortic vascular smooth muscle cells. Explicitly, crystals of approximately 1 m in diameter caused rapid rises in intracellular calcium concentration, their potency depending on t...

BACKGROUND Disturbed calcium-phosphorus balance significantly contributes to uraemic changes in large arteries. We examined the influences of high-calcium and high-phosphate intake on small artery tone in experimental renal insufficiency. METHODS Sixty-five rats were assigned to 5/6 nephrectomy (NTX) or sham operation. After 15 week disease progression, NTX rats were given high-calcium (3%), ...

To get complete information about the chemical composition and physicochemical principles underlying the formation of stone there is a need for more precise information. At present there is no single analytical procedure that provides an exact quantitative analysis of urinary calculi. In this present procedure it is assumed that only calcium oxalate monohydrate, hydroxyapatite, or magnesium amm...