Physiological regulations of energy balance and body weight imply highly adaptive mechanisms which match caloric intake to caloric expenditure. In the central nervous system, the regulation of appetite relies on complex neurocircuitry which disturbance may alter energy balance and result in anorexia or obesity. Deoxynivalenol (DON), a trichothecene, is one of the most abundant mycotoxins found ...

dissolved organic nitrogen (don) can react with disinfectants to produce numerous disinfectionbyproducts (dbps), particularly nitrogen-containing dbps (n-dbps), and produce serious adverse effectson public health. widely used biological processes in drinking water treatment can increase don in effluents,and enhance these ill effects. this study investigated don in a full-scale two-stage ozonati...

Deoxynivalenol (DON) is a mycotoxin produced by the plant pathogenic fungi Fusarium graminearum and F. culmorum. These and other closely related fungi cause a disease known as Fusarium head blight (FHB) in small grain cereals. Other mycotoxins produced by FHB-causing fungi include nivalenol, T-2 toxin, and zearalenone. Ingestion of mycotoxin-contaminated food and feed can lead to toxicosis in h...

fusarium head blight (fhb) or wheat scab is one of the destructive diseases that cause considerable loss in grain quality in cereal cultivated around the worldwide due to the production of trichotecen mycotoxin in the panicle. type b trichothecenes including nivalenol (niv), deoxynivalenol (don), 3-acetyl deoxynivalenol (3-acdon) and 15-deoxynivalenol (15-acdon) are considered to be major toxin...

Bensassi, F., Zarrouk, A., Gargouri-Kammoun, L., Hajlaoui, M.R., and Bacha, H. 2011. Quality of feed cereals in Tunisia: Natural occurrence of the mycotoxin deoxynivalenol. Tunisian Journal of Plant Protection 6: 11-19. In Tunisia, the contamination of cereal grains with mycotoxins is very common. Such a situation is chiefly favored by the Mediterranean climate of the country, which plays a cri...

Cereal-based food can be frequently contaminated by the presence of mycotoxins derived from Fusarium fungus, and, in particular, by deoxynivalenol (DON). Nowadays, analytical strategies for the detection of DON are well developed, but there are gaps for what concerns a correct identification, quantification and toxicological evaluation of the respective metabolites, mainly related to detoxifyin...

Dropa T., Hajšlová J., Lancová K., Burešová I. (2014): The effect of bread-making process on contents of key trichothecene mycotoxins: deoxynivalenol, T-2, and HT-2 toxins. Czech J. Food Sci., 32: 570–577. The fate of trichothecene mycotoxins deoxynivalenol (DON), T-2 and HT-2 toxins during the bread preparation and baking was investigated in order to obtain information about the influence of p...

Hajšlová J., Lancová K., Sehnalová M., Krplová A., Zachariášová M., Moravcová H., Nedělník J., Marková J., Ehrenbergerová J. (2007): Occurrence of trichothecene mycotoxins in cereals harvested in the Czech Republic. Czech J. Food. Sci., 25: 339–350. A large-scale survey of the natural occurrence of trichothecene mycotoxins in major cereals harvested in the Czech Republic was conducted during th...

Cereal infection by the broad host range fungal pathogen Fusarium graminearum is a significant global agricultural and food safety issue due to the deposition of mycotoxins within infected grains. Methods to study the intracellular effects of mycotoxins often use the baker's yeast model system (Saccharomyces cerevisiae); however, this organism has an efficient drug export network known as the p...

Mycotoxins are fungal secondary metabolites contaminating food and causing toxicity to animals and humans. Among the various mycotoxins found in crops used for food and feed production, the trichothecene toxin deoxynivalenol (DON or vomitoxin) is one of the most prevalent and hazardous. In addition to native toxins, food also contains a large amount of plant and fungal derivatives of DON, inclu...