نتایج جستجو برای: cancer cytogenetics
تعداد نتایج: 917117 فیلتر نتایج به سال:
1 Title: Hematologi β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity. Authors: Luis J. Leandro-García, Susanna Leskelä, Lucia Inglada-Perez , Iñigo Landa, Aguirre A de Cubas, Agnieszka Maliszewska, Iñaki Comino-Méndez, Rocío Letón, Álvaro Gómez-Graña, Raúl Torres, Juan Carlos Ramírez, Sara Alvarez, José Rivera, Constantino Martinez, Maria Luisa Lozano, Alber...
the variable expression in families. Of note, however, in the fact that the identification of the defect at the molecular level, recently published by Sherman and others, has made much of the molecular marker information presented here obsolete. Many of the confusing aspects of the reported pedigrees can now be explained by the observation of a variable number of CGG repeats at the fragile X lo...
Laryngeal squamous cell carcinoma (LSCC) is a common cancer of the upper respiratory tract. The cytogenetic and molecular events involved in the pathogenesis of LSCC are not well understood. In this study, a combined strategy of conventional cytogenetics, fluorescent in situ hybridization (FISH) and microsatellite polymerase chain reaction was performed to analyze the deletion of chromosome 6 i...
Aneuploidy or alteration in chromosome numbers is a characteristic feature in cancer that is generally a consequence of defective chromosome segregation during cell division. Molecular cytogenetic analyses have conferred substantial evidence with regards to the chromosomal architectures in cancer. Most importantly, the fluorescence in situ hybridization (FISH) technique that plays a leading rol...
Cytogenetic analyses of hematological neoplasms have proved to be relevant in the diagnosis, treatment, and prognosis of afflicted patients. Breast cancer (BC) cytogenetics is expected to contribute in the same fashion. Literature has shown that clone-specific chromosomal changes do occur in BC, yet, their clinical significance is unknown. Most of the studies have been conducted on patients wit...
When the discovery of giant banded, salivary chromosomes in Drosophila was made by Painter in 1934, it gave a tremendous impact to the cytological work carried out in Drosophila. This made it possible to identify the chromosomes individually and also to discern the specific segments of the chromosome. Followed by this, cytogenetics bloomed with the establishment of chromosome number in man as 4...
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