1. INTRODUCTION Clinical trials have identified effective new cancer therapies and screening strategies. Additional clinical trials are needed for further progress in cancer prevention, screening, and treatment. However, clinical trials raise ethical concerns because volunteers take on risk for the primary goal of advancing scientific knowledge and helping future patients. Moreover, the risks a...

PURPOSE The goal of this study was to examine the effect of a rural community clinical oncology program-based cancer-care intervention program that was launched to increase the number of rural patients with cancer enrolled in clinical trials. DESCRIPTION OF STUDY Five rural counties in eastern North Carolina served as intervention communities, and five rural counties in South Carolina served ...

INTRODUCTION Employee wellness programs (EWPs) have been used to implement worksite-based cancer prevention and control interventions. However, little is known about whether these programs result in improved adherence to cancer screening guidelines or how participants' characteristics affect subsequent screening. This study was conducted to describe cancer screening behaviors among participants...

Cancer Nanovaccines In article number 2104849, Mi Liu and co-workers demonstrate a simple universal method to prepare therapeutic preventive cancer nanovaccines based on tumor tissues/cells. Such show both potent efficacy in lung cancer, melanoma, breast cancer. This can be applied make tumor-cell-based for immunotherapy prevention.

In 1971, President Richard Nixon declared a war on cancer and signed the National Cancer Act. During the past several decades since this declaration, the nation has made extraordinary progress toward a more in-depth understanding of the molecular, cellular, and genetic changes resulting in cancer. We have also seen significant declines in overall and site-specific cancer mortality. This decline...

BACKGROUND Chemoprevention could significantly reduce cancer burden. Assessment of efficacy and risk/benefit balance is at best achieved through randomized clinical trials. METHODS At a periodic health examination center 1463 adults were asked to complete a questionnaire about their willingness to be involved in different kinds of preventive clinical trials. RESULTS Among the 851 respondent...

There are a lot of evidences on the beneficial effects mediated by exercise prevention not communicable diseases (NCDs) including different type cancer. The production circulating exerkines transported in exosomes represents novel pathway activated exercise. However, biological mechanisms that could explain role cancer have been fully elucidated. aim this mini-review is to provide an update bri...

As incoming President of the American Association for caused by cancer therapy. Although tertiary approaches do Cancer Research (AACR), I am delighted that the AACR publishes the journal Cancer Prevention Research and that this journal is meeting with great success, because I believe the AACR should continue to increase its efforts in the arena of cancer prevention. The past few decades in part...