esophageal squamous cell carcinoma is a rather common cancer in northern iran. incidence of adenocarcinoma of esophagus has an increasing trend in iran. co-existence of both cancers in one patient is very rare. we report a middle age woman from northern iran with a typical presentation of esophageal cancer, who was found to have a dual esophageal cancer. the disease was found in the advanced st...

background: attempts for early detection of gastric cancer have recently focused on host's genetic susceptibility factors and gene-environment interactions. we have, herein, studied the association of mthfr c677t single nucleotide polymorphism (snp) and its interaction with helicobacter pylori infection, smoking, age and gender on the risk of gastric cancer among an iranian population. met...

background : although, family history of cancer is an important risk factor for upper gastrointestinal cancers development, but limited information is available on the upper gastrointestinal cancers associated with family history in iran. the purpose of this study was to define upper gastrointestinal cancers risk associated with family history of cancer. methods : this study was conducted as a ...

to establish a comprehensive picture of the relationship between glutathione s-transferase omega 2 (gsto2; mim: 612314) gene n142d variant (rs. 156697) and breast cancer risk, the present meta-analysis was carried out. studies published up to july 2012 with information about gsto2 polymorphism and breast cancer risk were identified using several electronic databases. we identified 4 eligible st...

background : the age standardized incidence rates of esophageal cancer in women and men in iran have the fifth and eighth ranks, respectively. due to the high incidence rate of esophageal cancer and the necessity of knowledge of its geographical distribution, the incidence of this cancer was mapped at province and county levels in the present study. methods: the study population of this empiric...

Objective(s):Genome-wide association studies have identified a number of genetic variants of telomerase reverse transcriptase (TERT), cleft lip and palate transmembrane1-like (CLPTM1L) associated with the risk of bladder cancer. Rs401681 polymorphism in TERT-CLPTM1L was of special interest for bladder cancer risk, whereas the results were inconclusive. Materials and Methods:Publications illustr...

background: life style is an important element to prevent the cancer. therefore, this study aimed to determine life style risk factors of tehran citizens as well as to prevent cancer. methods: this study is a descriptive - analytic research with sample size of 2500 tehran citizens. the study data was collected via a questionnaire that contained 2 parts: demographic and questions related to life...

background: turkey, especially the northern part of it, was one of the countries which were contaminated by the chernobyl accident.  rize is a city located in the northeastern district of turkey which was heavily influenced by the chernobyl nuclear accident. materials and methods: in this study, the activity concentrations of natural (226ra, 232th, 40k) and artificial (137cs) were measurements ...

background : this study evaluated the role of family history of cancer and gynecologic factors in relation to the etiology of ovarian cancer in a low socioeconomic population in iran. methods : from 2007-2009 we conducted a screening program on women with insurance coverage provided by the imam khomeini relief foundation. a total of 26788 women participated in this study of whom 76 cases had ov...