Most of the deaths in world happen due to Cancer. It is a disease which cells our body organs or tissues grow an undisciplined way turn can harm normal and body. These very smartly trick immune system so that cancerous are kept alive not destroyed. In human body, tumors be classified into three types: cancerous, non-cancerous, pre-cancerous. Timely identification cancer helpful many ways. As it...

OBJECTIVES The benefits of PSA (prostate specific antigen)-testing in prostate cancer remain controversial with a consequential need for validation of additional biomarkers. We used highly standardized reverse-transcription (RT)-PCR assays to compare transcript levels of 10 candidate cancer marker genes - BMP6, FGF-8b, KLK2, KLK3, KLK4, KLK15, MSMB, PCA3, PSCA and Trpm8 - in carefully ascertain...

OBJECTIVE The purpose of the study is to highlight the use of gamma-glutamyl transpeptidase (GGT) as salivary enzyme tumor marker and assess the activity and concentration of GGT in precancerous and cancer patients and compare it with the normal control. MATERIALS AND METHODS Individuals in the age group of above 20 years were included in the study. In this study, salivary GGT was analyzed in...

The public can be defined as a mosaic consisting of various ethnic, religious and other social groups, hence the definition of public includes each individual persona. Public opinion is the voice of such public and is, therefore, considered a worthy element in political and economic discourse. Media can do much in providing education necessary for informing the public about cancerous substances...

recent studies on wavelet transform and fractal modeling applied on mammograms for the detection of cancerous tissues indicate that microcalcifications and masses can be utilized for the study of the morphology and diagnosis of cancerous cases. it is shown that the use of fractal modeling, as applied to a given image, can clearly discern cancerous zones from noncancerous areas. in this paper, f...

Over the past decade, investigators have increased their understanding of the genetic alteration that transforms a normal cell into one that is cancerous. One gene found to play a critical role in preventing the cancerous transformation of a cell is a tumor suppressor gene known as p53. If this gene is deactivated, a cell will become cancerous. Therefore, methods for reintroducing this gene bac...

In this study, we measured free radicals and thiobarbituric acid-reactive substances (TBARS) in hepatocellular carcinoma and in non-cancerous liver parenchyma. There was a higher concentration of free radicals in malignant tissue than in non-cancerous tissue. In contrast, the level of TBARS was significantly (P < 0.01) lower than non-cancerous liver parenchyma. These paradoxical results suggest...

Understanding cell proliferation mechanisms has been a long-lasting goal of the scientific community and specifically of cancer researchers. Previous genome-scale studies of cancer proliferation determinants have mainly relied on knockdown screens aimed to gauge their effects on cancer growth. This powerful approach has several limitations such as off-target effects, partial knockdown, and mask...

Thrombospondin (TSP)-2 is known to be an endogenous negative regulator of vascularization in human cancer. However, it is unclear whether TSP-2 expression is related to neovascularization and prognosis in non-small cell lung cancer. In this study, we quantitatively examined the expression of TSP-2 mRNA by real-time reverse transcription-polymerase chain reaction (RT-PCR) in 102 pulmonary adenoc...

objective: azadirachta indica (neem) has been used traditionally for many centuries. some impressive therapeutic qualities have been discovered. however, the therapeutic effect of neem leaf extract in 4t1 breast cancer has not been documented. the purpose of the present study is to investigate the therapeutic effect of ethanolic neem leaf extract in an in vivo 4t1 breast cancer model in mice. m...