Abstract This Invited Editorial towards the Special Issue on Hepatobiliary and Pancreatic Surgery highlights global problem of young-onset cancers. The paucity data pancreatobiliary cancers is presented in context its relevance to India (and large component adults at-risk age group for these cancers). In face limited information underlying cause cancers, author draws attention evidence from col...

Despite the plethora of "oncogenes" and "tumor suppressor genes," the hypothesis that cancer is usually the result of genomic mutations may be wrong. We should at least examine the alternative hypothesis, for which there is considerable evidence, that mutations do not commonly beget cancer, but rather that cancer phenotypes result from confused or aberrant patterns of normal-gene expression; th...

background: the earlier atomic bomb explosion in hiroshima and nagasaki, and three worth mentioning nuclear accidents - detonation at fukushima daiichi nuclear plant, chernobyl nuclear fallout and an accident at three mile island nuclear power plant have made us more worried about the secure exploitation of nuclear energy. the central focus of this paper is to review radiation-mediated health e...

The review analyzes some parameters of CBA mice-males as model spontaneous carcinogenesis characterizing adhesive and adaptive disorders. A weakening the hepatocytes mutual adhesiveness force was noted already in early ontogenesis (5–10 days postnatal development). This violation persisted enhanced during hepatocarcinogenesis. decrease β2 leukocyte integrins LFA-1 Mac-1 expression on peripheral...

Background & Objectives: Colon cancer is currently of high incidence and mortality rate. Identifying the factors influencing its prognosis can be very beneficial to its clinical treatment. Recent studies have shown that lymph nodes ratio can be considered as an important prognostic factor. The aim of the present study is to investigate the effect of this factor on the prognosis of the ...

Introduction: Alpha particle emitters are very damaging and harmful when entering into the human body ,if   ingested or inhaled , swallowed or absorbed  into the lungs or bloodstream . Uranium (238U), Radium (226Ra) and Radon (222Rn) are typical alpha-particle emitters. Material and Methods: we measured the level of alpha particles emitted from 222Rn, 226Ra, and 238U in blood samples of 10 can...