Factors like oral and denture hygiene, presence of saliva, age of the denture, and degree of colonization with Candida albicans are to be evaluated as local contributing factors for causing denture stomatitis. 100 patients aged 30 to 70 years were selected for the study. Among these, 70 patients were labeled test group showing signs of stomatitis and 30 patients as control group as they showed ...

There is a wide range of variability in the reported frequencies of fungal colonization in NICUs due to several factors. Inconsistencies in surveillance culture policies make it difficult to compare the incidence rates of different settings and institutions: as a result, NICUs performing weekly (or semiweekly) cultures for each patient will claim higher incidence rates of colonization than thos...

Secreted aspartyl proteinases are putative virulence factors in Candida infections. Candida albicans possesses at least nine members of a SAP gene family, all of which have been sequenced. Although the expression of the SAP genes has been extensively characterized under laboratory growth conditions, no studies have analyzed in detail the in vivo expression of these proteinases in human oral col...

A novel denaturing high-performance liquid chromatography (DHPLC)-based technique allows rapid high-resolution analysis of PCR products. We used this technique for unequivocal molecular identification of seven Candida species. We show the application of this PCR/DHPLC approach for direct detection and identification of yeast species from blood cultures and for detection of Candida colonization ...

Saccharomyces boulardii has been and continues to be extensively used as a probiotic, with only rare associations with fungemia. This study evaluated the virulence of this yeast when given as a probiotic, and its role in preventing gastrointestinal (GI) colonization by Candida. Adult male Crl:CD1 (ICR) BR mice were given S. boulardii orally in three different doses or normal saline for 14 days....

BACKGROUND Wearing a dental prosthesis is known to increase oral candidal colonization and predispose the wearer to oral candidosis. Denture wearers frequently use fingers to take the prosthesis out of their mouth. Oral Candida, if present may contaminate wearer's finger. The objective of this study was to investigate the simultaneous candidal colonization of oral cavity and fingertips of compl...

BACKGROUND Fungal infections are common cause of morbidity and mortality in very low birth weight Infants OBJECTIVES To evaluate the efficacy of prophylactic Fluconazole in preventing fungal colonization and invasive fungal infection in VLBW infants. DESIGN Prospective, randomized, double blind placebo controlled clinical trial. SETTING Tertiary level Neonatal intensive care unit. SUBJE...

BACKGROUND Gelclair is an oral lubricating gel used in the management of oral mucositis (OM). We evaluated its efficacy, tolerance and impact on oral cavity microbial colonization in patients with OM after allogeneic hematopoietic stem cells transplantation. MATERIAL/METHOD Gelclair was administered in a group of 22 patients with active OM. A control group of 15 patients used other rinsing so...

INTRODUCTION Pseudomonas aeruginosa is a frequent cause of ventilator-acquired pneumonia (VAP). Candida tracheobronchial colonization is associated with higher rates of VAP related to P. aeruginosa. This study was designed to investigate whether prior short term Candida albicans airway colonization modulates the pathogenicity of P. aeruginosa in a murine model of pneumonia and to evaluate the e...

Oral yeast carriage was studied in 312 Mexican subjects. Candida albicans was the most frequent species, but other Candida spp. were isolated from 16.5 to 38.5% of patients. Colonization did not correlate with CD4+ number or viral load, but highly active antiretroviral therapy reduced the frequency of candidiasis. Most isolates were susceptible to fluconazole, but 10.8% were resistant to one or...