Seven yeast strains isolated from natural substrates of Thailand were found to represent two novel species of Candida, an ascomycetous anamorphic genus. Three strains, ST-233, ST-259 and ST-260, isolated from insect frass and plant leaves were found to represent a single novel species related to Metschnikowia agaves in a tree based on the D1/D2 domain sequences of the 26S rRNA genes. This speci...

Antonio Marcondes Lerario, Luciana Pinto Brito, Beatriz Marinho Mariani, Maria Candida B V Fragoso, Marcel Autran Cesar Machado, Roberto Teixeira I Unidade de Endocrinologia do Desenvolvimento, Laboratório de Hormônios e Genética Molecular (LIM-42), Disciplina de Endocrinologia, Hospital das Clı́nicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. II Laboratório de Inv...

KOH: potassium hydroxide INTRODUCTION Aspergillus sp, Candida sp, and zygomycoses can disseminate rapidly in an immunocompromised host, causing significant morbidity and mortality. Serum testing, tissue biopsy, and culture are used to confirm a suspected diagnosis, but waiting for results may delay initiation of life-saving treatment. We report a case of disseminated aspergillosis presenting wi...

Estrogen deficiency around menopause can cause growth of abnormal flora leading to infections. The aim of the study was to assess the prevalence of bacterial vaginal infections among the asymptomatic pre and postmenopausal women. High vaginal swab samples were collected and the microorganisms were identified. Their antibiotic susceptibility pattern was noted. Escherichia coli, Staphylococcus au...

We reported herein the synthesis, antifungal activity, docking and in silico ADME prediction studies of four novel series of sulfones 6a-f, 8a-c, 10a-f and 12a-c. All the newly synthesized sulfones were tested against four strains of Candida (including fluconazole-resistant Candida), two strains of Aspergillus, two dermatophytic fungi (Trichophytons mentagrophyte and Microsporum canis) and Sync...

A long lasting, protective and film forming HPCH-based medical device was developed and tested in a novel in vitro human nail infection model. HPCH-treated and untreated human distal fingernail fragments were disposed on the culture surface of Trychophyton rubrum, T. mentagrophytes, Scopulariopsis brevicaulis or Candida parapsilosis. After incubation for one or three weeks, the fragments were c...

cheese 13 RUNNING TITLE: Candida cabralensis sp. nov. from Cabrales cheese 14 15 Abstract 24 Three yeast strains, 1AD8, 3AD15 and 3AD23, belonging to a previously unknown 25 yeast species were isolated from two independent batches of the Spanish blue-veined 26 Cabrales cheese, a traditional cheese manufactured without the addition of starter and 27 mould cultures. Physiological characterisation...

OBJECTIVES Novel highly functionalized bis cyclohexenone ethyl carboxylates 7-12 were designed, synthesized and their structures were elucidated by their elemental analysis, MS, FT-IR, one-dimensional 1H, and 13C NMR spectroscopic data. MATERIALS AND METHODS All the synthesized compounds 7-12 were tested for their in vitro antifungal activities against Candida sp. namely Candida albicans, Can...