نتایج جستجو برای: capillary flow
تعداد نتایج: 513793 فیلتر نتایج به سال:
Introduction: A hallmark of sepsis is early onset microvascular dysfunction. However, the mechanism responsible for maldistribution of capillary blood flow is not understood. Evidence suggests red blood cells (RBC) can sense local oxygen (O2) conditions and signal the vasculature, via adenosine triphosphate (ATP), to increase capillary flow. We hypothesized that sepsis impaired microvascular au...
The aim of this study was to determine if skeletal muscle capillary density is lower in patients with peripheral artery disease (PAD) and if capillary density relates to functional limitations. PAD patients with intermittent claudication (IC) have a decreased exercise tolerance due to exercise-induced muscle ischemia. Despite the apparent role diminished arterial flow has in this population, th...
An explanatory computational model is developed of the contiguous areas of retinal capillary loss which play a large role in diabetic maculapathy and diabetic retinal neovascularization. Strictly random leukocyte mediated capillary occlusion cannot explain the occurrence of large contiguous areas of retinal ischemia. Therefore occlusion of an individual capillary must increase the probability o...
Using radioactive microspheres, mucosal and muscular capillary blood flow have been measured in the rumen, reticulum, and omasum of conscious sheep. Total forestomach capillary blood flow (7.7 ml min(-1) kg body wt(-1)) was about 7% of cardiac output; 95% of the flow was in the mucosa and only 5% in muscle layers. Blood flow in the rumen was 6 times higher than in the reticulum and 4.4 times hi...
A better knowledge of the flow and pressure distribution in realistic microvascular networks is needed for improving our understanding of neurovascular coupling mechanisms and the related measurement techniques. Here, numerical simulations with discrete tracking of red blood cells (RBCs) are performed in three realistic microvascular networks from the mouse cerebral cortex. Our analysis is base...
Simulation of Qualitative Peculiarities of Capillary System Regulation with Cellular Automata Models
Peripheral circulation can be divided in two components: continuous one, which includes continual fluctuation of muscular vessels diameters; and discrete one, which is caused by opening and closing of pre-capillary sphincters causes the activation-deactivation of capillaries. The state of each capillary sphincter depends on concentration of tissues vasodilator metabolites in the neighborhood of...
The dynamics of capillary climb of a wetting liquid into a porous medium that is opposed by gravity force is studied numerically. We use the capillary network model, in which an actual porous medium is represented as a network of pores and throats, each following a predefined size distribution function. The liquid potential in the pores along the liquid interface within the network is calculate...
We present a stable numerical scheme for modelling multiphase flow in porous media, where the characteristic size of the flow domain is of the order of microns to millimetres. The numerical method is developed for efficient modelling of multiphase flow in porous media with complex interface motion and irregular solid boundaries. The Navier–Stokes equations are discretised using a finite volume ...
Nailfold capillaroscopy (NC) allows non-invasive imaging of systemic sclerosis (SSc) related microvascular disease. We have developed a state-of-theart NC system that enables fast, panoramic imaging of the whole nailfold at highmagnification, and incorporates novel software to make fully automated estimates of capillary structure and blood flow velocity. We present the first results of a study ...
JOHNSON, PAUL C.,JON BLASCHKE, KENNETH S. BURTON, AND JOE H. DIAL. Infruence of Jzozo variations on capillary hematocrit in mcsenter-y. Am. J. Physiol. 221(l): 105-l 12. 1971.~Red cell spacing was measured on line in mesenteric capillaries of the cat by counting red cells passing through the capillary and simultaneously measuring red cell velocity. Most capillaries had reasonably stable hematoc...
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