Serine hydrolase inhibitors, which facilitate enzyme function assignment and are used to treat a range of human disorders, often act by an irreversible mechanism that involves covalent modification of the serine hydrolase catalytic nucleophile. The portion of mammalian serine hydrolases for which selective inhibitors have been developed, however, remains small. Here, we show that N-hydroxyhydan...

Monosulphides of O-phenyl-N-substituted phenylcarbamates were prepared by the reaction between Ophenyl-N-substituted phenylcarbamates and sulphur dichloride while the corresponding disulphides were prepared by the reaction between O-phenyl-Nsubstituted phenylcarbamates and sulphur monochloride. The synthesized compounds were characterized by elemental analysis, thin layer chromatography (TLC), ...

J. Ecan. Entomd 79: 14521458 (1986) ABSTRACï Resistance mechanisms of a strain (MSE) of Culex pipiens L., collected in sauthern France in 1979 and highiy resistant to chlorpynfos. were investigated by comparing the resistance characteristics to vanous organophasphates and carbamates in the absence or presence of synergists and determining the biochemical characteristics of four enzymes (esteras...

The use of polyurethanes and, therefore, the quantity its scrap are increasing. Considering thermoset characteristic most polyurethanes, circular recycling method is by means chemical depolymerization, for which glycolysis finding way into industry. main goal polyurethane to recover polyols used, but only limited attempts were made toward recovering aromatic dicarbamate residues and derivates f...

The Cover Feature shows one of four potential energy surfaces generated from our rotation-inversion study tertiary carbamates and highlights two the eight possible transition state pathways between ensembles E- Z-minima. More information can be found in Research Article by Brian Jameson Rainer Glaser.

In the title compound, C(13)H(21)N(3)O(4)S, the mean plane of the -N(H)-C(=O)-O- group of the carbamate unit forms a dihedral angle of 64.7 (2)° with the mean plane of the -C-C(=O)-O- group of the ester unit. In the crystal, mol-ecules are linked by N-H⋯O=C hydrogen bonds, forming chains along the c-axis direction.