a few analogues of atevirdine or 1-[(5-methoxyindol-2-yl) carbonyl]-4-[3- (ethylamino)-2-pyridyl] piperazine – an anti-hiv belonging to non-nucleoside reverse transcriptase inhibitors were synthesized and evaluated for anti-hiv activity. replacement of indolyl moiety with 2-alkylthio-1-benzyl-5-imidazolyl substituent afforded 1-[2-(alkylthio-1-benzyl-5-imidazolyl) carbonyl]-4-[3-(isopropylamino...

Oximes are highly crystalline materials and oximation is very efficient method for characterization and purification of carbonyl compounds. These compounds not only represent a useful series of derivatives of carbonyl compounds but also may be used as intermediates for the preparation of amides by the Beckmann rearrangement [1], nitrones [2], hydroximinoyl chlorides, nitrile oxide [3] and chi a...