PURPOSES Pulse CO-oximetry (Rad-57; Masimo Corp, Irvine, CA) has been available since 2005. To date, all published clinical studies have focused on clinical reliability and whether the device enhances case finding through screening of various populations. This study examines whether use of pulse CO-oximetry shortens the time to diagnosis and treatment of patients with carbon monoxide (CO) poiso...

PURPOSE Inhalation injury is one of the most severe morbidity and mortality factors in burn patients. The purpose of this study is to analyze the impact of inhalation injury to the prognosis of burn patients and to investigate the relationship between the inhalation injury assessment and the prognosis of patients. METHODS Bronchoscopy was performed in 170 patients who had the suspicion of inh...

BACKGROUND Because treatment modalities for carbon monoxide (CO) poisoning, especially normobaric oxygen and hyperbaric oxygen therapies, have limited effects and hyperbaric oxygen is not available at the scene where treatment is most needed, we conducted a study to determine and compare rates of carboxyhemoglobin (COHb) dissociation achieved in human in vitro blood samples under light radiatio...

We read with great interest the study in CHEST by Dr. Yasuda and colleagues (June 2004)1 elucidating the role of arteriovenous carboxyhemoglobin (a-vHb-CO) difference in patients with fevers of unknown origin. The authors reported that the presence of an a-vHb-CO difference may be a useful indicator to differentiate between pulmonary and extrapulmonary diseases. This hypothesis was generated fr...

INTRODUCTION Carbon monoxide (CO) is a colorless, odorless gas produced as a by-product of incomplete combustion, and a common source is the fuel used for heating water in homes. The clinical presentation of CO poisoning may be mild, moderate, or severe. CASE PRESENTATION This paper describes carbon monoxide (CO) poisoning in a 15-year-old child who suffered from severe cardiopulmonary compro...

Acute Exposure Guideline Levels (AEGLs) are derived to protect the human population from adverse health effects in case of single exposure due to an accidental release of chemicals into the atmosphere. AEGLs are set at three different levels of increasing toxicity for exposure durations ranging from 10 min to 8 hours. In the AEGL-setting for methylene chloride specific additional topics had to ...

INTRODUCTION The reference values (RV) of biological indicators are used in the interpretation of the results of such indicators in individuals occupationally exposed to chemical agents. The Brazilian Group for the Establishment of Reference Values has worked on these definitions for the purpose of establishing RVs for several bioindicators in various regions of the country. In the present stud...

BACKGROUND Carbon monoxide (CO) is produced endogenously, and can also be acquired from many exogenous sources: ie. cigarette smoking, automobile exhaust. Although toxic at high levels, low level production or exposure lends to normal physiologic functions: smooth muscle cell relaxation, control of vascular tone, platelet aggregation, anti- inflammatory and anti-apoptotic events. In pregnancy, ...

Historically, and at present, carbon monoxide is a major gaseous poison responsible for widespread morbidity and mortality. From threshold to maximal nonlethal levels, a variety of cardiovascular changes occur, both immediately and in the long term, whose homeostatic function it is to renormalize tissue oxygen delivery. However, notwithstanding numerous studies over the past century, the litera...

Objective: To characterize the cardiorespiratory function and state of oxidative stress resulting from exposure towood smoke in women who live at high altitude (3,850 m a.s.l.). Materials methods: An observational case-series study. The was analyzed, thebiomarkers malondialdehyde (MDA) carboxyhemoglobin (COHb) were quantified. Measures centraltendency dispersion determined. statistical methods ...