In the course of their work on the carcinogenic action of oils and tars on mouse's skin, Twort and Twort (4,5) observed that addition of anhydrous lanolin often led to a reduction in neoplastic response. The inhibitory effect was greater than that obtained with benzene as diluent, and also occurred when lanolin was applied separately to the skin during the intervals between paintings. In view o...

The article examines the harm caused by benzapyrene to environment and human health. Being a carcinogen, accumulating in body, it has mutagenic, embryotoxic, hematotoxin effect. Regulations require removal of contaminated soil from construction site with subsequent disposal. disinfection methods are analyzed.

Helicobacter pylori is an important pathogen to detect and eradicate, particularly as it a known carcinogen. With rising antibiotic resistance control has become challenging. Here the authors propose new algorithm for primary care discuss managing treatment failure.

The development of oral squamous cell carcinoma (SCC) shows a positive correlation with the carcinogen exposure that occurs during tobacco and alcohol use. The purpose of this study was to investigate whether the naturally occurring chemopreventive agent, curcumin, modulates expression and function of carcinogenmetabolizing enzymes in human keratinocytes isolated from oral SCC tumors. Dose-resp...

The covalent binding of an ultimate carcinogen to the DNA bases or phosphate groups creates a premutational lesion that in vivo is processed by the repair, replication and recombination enzymes, and eventually may be converted into a mutation. Being interested in the way that an initial premutational event is converted into a stable heritable mutation, we have sequenced stable mutations in a ge...