at necropsy of a five-year-old sheep, a pear shaped, lobular yellow-brownish mass measuring about 12 ×15 × 20 cm was found to involve the right hepatic lobe. microscopic examination revealed two trabecularand solid patterns of neoplastic hepatocytes. in solid pattern, there were numerous tumoral giant cells thatcontain one or more large hyperchromatic bizarre-shaped nuclei scattered among clust...

conclusions we showed that in treatment of patients with unresectable hepatocellular carcinoma, tace significantly improved the disease and the overall survival rate. also, we introduce the tumor size, serum alp level, and number of liver involved segments as prognostic factors of the procedure. finally, tace can be recommended as the initial treatment for unresectable hcc patients. background ...

results the mean age at the time of diagnosis was 54 years (range, 28 - 74). cause-specific survival rates of the entire group were 92%, 87% and 82%, at two, three and five years, respectively. the five-year cause-specific survival rates for grades one, two and three were 98%, 88% and 68%, respectively. multivariate analysis revealed that age, depth of myometrial invasion, involvement of ovarie...

background & objectives: tumor diathesis (td) is defined as granular proteinaceous precipitates on slide surface of cytologic smears. it is found in the background of smears of invasive carcinoma but not in all cases. the aim of present study was to determine the prevalence of td in cervicovaginal smears from patients with uterine cervix carcinoma. methods: cytological smears and histologi...

abstract bronchoalveolar carcinoma presenting as non-resolving consolidation is an uncommon presentation. the typical presentation of bronchoalveolar carcinoma is asymptomatic (solitary nodule) and remains without symptoms even as disease disseminates. we report a case of bronchoalveolar carcinoma presenting as non-resolving consolidation in a young male with productive cough, exertional breath...

abstract background: screening is a necessity for country health systems. in undeveloped countries that have no screening programs, cervical carcinoma is one of the major causes of mortality and morbidity. although cervical cancer is preventable it is poorly controlled in some countries. the main cause of it is unawareness of people from cervical cancer and screening methods. methods: the targe...

context from the 1970s till the mid 1990s, hepatitis b was the most common etiological factor for hepatocellular carcinoma (hcc) in pakistan. afterwards, a shift in hcc etiology was observed with a steady rise in hepatitis c virus (hcv) related hcc cases. hcv-3a, which is the most prevalent genotype, is also most frequent in hcv related hcc. there was an increase in the proportion of non-b non-...

abstract: primary adenoid cystic carcinoma (acc) of bartholin’s gland is a rare gynecologic malignancy. we report a case of locally advanced acc of bartholin’s gland. a 62-year-old presented with left bartholin’s gland carcinoma and underwent left radical vulvectomy,left-sided inguinal-femoral lymph node dissection, posterior pelvic exenteration, and pedicle abdominal muscle flap. on her 3 mont...

sunitinib is an oral tyrosine kinase inhibitor which prevents tumor growth and metastatic progression. it was approved for treatment of advanced renal cell cancer, gastrointestinal stromal tumor and advanced pancreatic neuroendocrine tumors. it has several adverse reactions on multi organ systems including hematologic system. although the neutropenia and thrombocytopenia commonly happens as gra...