Ascending aortic aneurysms are usually treated with graft replacement under cardiopulmonary bypass. However, if a candidate for off-pump coronary artery bypass grafting has an enlarged ascending aorta, surgeons may consider wrapping it without cardiopulmonary bypass. Here, we report a 78-year-old female who underwent successful wrapping of the ascending aorta concomitant with off-pump coronary ...

A 72-year-old man underwent aortic valve replacement and coronary artery bypass graft using cardiopulmonary bypass with right axillary artery cannulation. After undraping, petechial and subcutaneous hemorrhage with blister formations were found in right upper extremity. Axillary artery cannula was considered to compress right subclavian and disturb venous return in the right subclavian vein, wh...

Background/Introduction Acute kidney injury (AKI) occurs in up to 30% of patients undergoing coronary artery bypass grafting. Development of kidney injury is associated with high overall mortality and a more complicated hospital course. Cardiopulmonary bypass is considered as one of the major risk factors for developing AKI. Off-pump coronary artery bypass (OPCAB) grafting eliminates the need f...

Pupil diameter is used during anaesthesia to assess depth of anaesthesia and indicate cerebral hypoxia. This is especially so during cardiac bypass when other autonomic signs cannot be monitored. We have used a pupillometer to determine the effect of cardiopulmonary bypass on the pupil. We have also investigated if any effect was caused by washout of opioid from the central nervous system by al...

Blood flow velocity of the middle cerebral artery was monitored during cardiopulmonary bypass procedures by means of transcranial Doppler ultrasonography. Our investigation was carried out in a group of 16 patients with severe carotid stenosis or occlusion and in a control group of 42 patients with no or stenosis of less than 50% local diameter reduction. After onset of cardiopulmonary bypass, ...

We have developed and report on a simplified cardiopulmonary bypass technique for experiments on implantable ventricular assist devices in calves. We used an electromechanical implantable ventricular assist device with a double cylindrical cam in three calves. Cannulas for the ventricular assist system were designed to be inserted between the left atrium and the descending aorta. We used the ou...

Since 1953 when Dr. John Gibbons, Jr. and colleagues first successfully used cardiopulmonary bypass to perform an open mitral comissurotomy, the technology of the cardiopulmonary bypass (CPB) circuit and the physiologic management of patients during extracorporeal circulatory support have undergone a tremendous evolution. Despite major technologic advances and half a century of experience with ...

PURPOSE Cardiopulmonary bypass is known to alter propofol pharmacokinetics in patients undergoing cardiac surgery. However, few studies have evaluated the impact of these alterations on postoperative pharmacodynamics. This study was designed to test the hypothesis that changes in propofol pharmacokinetics increase hypnotic effects after cardiopulmonary bypass. METHODS Twenty patients schedule...

OBJECTIVE Neonatal cardiac surgery with cardiopulmonary bypass is often complicated by morbidity associated with inflammation and low cardiac output syndrome. Hydrocortisone "stress dosing" is reported to provide hemodynamic benefits in some patients with refractory shock. Development of cardiopulmonary bypass-induced adrenal insufficiency may provide further rationale for postoperative hydroco...