BACKGROUND Youth have residual thymic tissue and potentially greater capacity for immune reconstitution than adults after initiation of combination antiretroviral therapy (cART). However, youth face behavioral and psychosocial challenges that may make them more likely than adults to delay ART initiation and less likely to attain similar CD4 outcomes after initiating cART. This study compared CD...

BACKGROUND Resuscitation situations are high risk and high stress, and delays in care can have significant influences on outcomes. Standardization of care protocols and equipment is postulated to decrease some of the stress and risk. The objective of this study was to document increased efficiency in finding resuscitation equipment in a standardized resuscitation cart. METHODS A new standardi...

Storage device performance prediction is a key element of self-managed storage systems and application planning tasks, such as data assignment and configuration. Based on bagging ensemble, we proposed an algorithm named selective bagging classification and regression tree (SBCART) to model storage device performance. It can improve the accuracy of a single CART model. In contrast with CART mode...

INTRODUCTION The objective of this analysis was to identify points of disruption within the prevention of mother-to-child transmission (PMTCT) continuum from combination antiretroviral therapy (CART) initiation until delivery. METHODS To address this objective, the electronic medical records of all antiretroviral-naïve adult pregnant women who were initiating CART for PMTCT between January 20...

INTRODUCTION After achieving undetectable HIV-RNA on cART, on cessation, HIV-RNA rebounds to pre-treatment values for the majority due to the presence of an inaccessible viral reservoir. There is some evidence that cART during primary HIV infection (PHI) limits the reservoir size, optimizing the chance of maintaining viral control off cART. Data are required to predict possible viral controller...

OBJECTIVE We aimed to evaluate clinical and immunological outcomes of paediatric patients receiving combination antiretroviral therapy (cART) enrolled in The AIDS Support Organization (TASO) Uganda national HIV/AIDS programme. DESIGN Observational study of patients (age <14 years) enrolled in 10 clinics across Uganda for which TASO has data. METHODS We extracted patient demographic, immunol...

Certified public accounts’ (CPAs) audit opinions of going concern are the important basis for evaluating whether enterprises can achieve normal operations and sustainable development. This study aims to construct prediction models help CPAs auditors make more effective/correct judgments on opinion decisions by deep learning algorithms, using following methods: neural networks (DNN), recurrent n...

Cocaine- and amphetamine-regulated transcript (CART) codes for a neuropeptide system with a number of biological roles. The high conservation of CART across species suggests that it has an important role in mammalian physiology. CART is widely expressed in the central nervous system and the periphery, but is particularly concentrated in the hypothalamus. CART peptides, particularly CART (55-102...

OBJECTIVE Rates of AIDS defining event (ADE), serious ADE and death by CD4 and HIV RNA categories before and after combination antiretroviral therapy (cART) initiation are lacking for high CD4 counts. METHODS Event rates were estimated within CD4 cell strata using a Poisson regression model adjusting for sex, exposure category, age, and current HIV RNA (<4, 4-4.99, > or =5 log copies/ml), and...

Concatenative speech synthesis systems attempt to minimize audible discontinuities between two successive concatenated units. In unit selection concatenative synthesis, a join cost is calculated that is intended to predict the extent of audible discontinuity introduced by the concatenation of two specific units. A study was conducted that used human perceptual data on the detectability of mid-v...