نتایج جستجو برای: catechols

تعداد نتایج: 714  

Journal: :Acta biochimica Polonica 2004
Georgios I Panoutsopoulos Christine Beedham

Molybdenum-containing enzymes, aldehyde oxidase and xanthine oxidase, are important in the oxidation of N-heterocyclic xenobiotics. However, the role of these enzymes in the oxidation of drug-derived aldehydes has not been established. The present investigation describes the interaction of eleven structurally related benzaldehydes with guinea pig liver aldehyde oxidase and bovine milk xanthine ...

Journal: :Applied and environmental microbiology 2006
Maria F Carvalho Maria Isabel M Ferreira Irina S Moreira Paula M L Castro Dick B Janssen

The aerobic metabolism of fluorobenzene by Rhizobiales sp. strain F11 was investigated. Liquid chromatography-mass spectrometry analysis showed that 4-fluorocatechol and catechol were formed as intermediates during fluorobenzene degradation by cell suspensions. Both these compounds, unlike 3-fluorocatechol, supported growth and oxygen uptake. Cells grown on fluorobenzene contained enzymes for t...

2012
M. S. Arani

Introduction The number of natural and synthetic 2H-pyran-2-one derivatives has been reported to exert notably the potential biological activity [1] and medicinal application such as: anticancer activity [2] hepatoprotective activity [3]. On the other hand, catechol derivatives are promising group of compounds worthwhile for further investigation, which may lead to the discovery of selective ac...

Journal: :PLoS Pathogens 2009
Katherine C. Yam Igor D'Angelo Rainer Kalscheuer Haizhong Zhu Jian-Xin Wang Victor Snieckus Lan H. Ly Paul J. Converse William R. Jacobs Natalie Strynadka Lindsay D. Eltis

Mycobacterium tuberculosis, the etiological agent of TB, possesses a cholesterol catabolic pathway implicated in pathogenesis. This pathway includes an iron-dependent extradiol dioxygenase, HsaC, that cleaves catechols. Immuno-compromised mice infected with a DeltahsaC mutant of M. tuberculosis H37Rv survived 50% longer than mice infected with the wild-type strain. In guinea pigs, the mutant di...

Journal: :Archives of biochemistry and biophysics 1998
X Huang R Xu M D Hawley T L Hopkins K J Kramer

The metabolism of catechols often involves their oxidation to quinones and subsequent nucleophilic addition reactions with sulfur-containing compounds. Adducts formed during these reactions may play important roles in many biological systems. We have studied the electrochemical oxidation of N-acetyldopamine (NADA) and N-beta-alanyldopamine (NBAD) in the presence of two sulfur-centered nucleophi...

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