BACKGROUND The latissimus dorsi myocutaneous flap and implant breast reconstruction procedure has undergone many refinements over its lifetime. In fact, the authors have made many aesthetic and technical refinements to their own approach to breast reconstruction. OBJECTIVES The authors review the historical progression of latissimus flap and breast reconstruction techniques and compare these ...

Background. Autologous dermal sling with wise pattern skin reducing mastectomy allows one-stage implant reconstruction in women with large and ptotic breasts needing mastectomy for cancer or risk reduction. However, this technique is not suitable for women who lack ptosis and also carries risk of T-junction breakdown. Method. We have performed one-stage nipple sparing mastectomies with implant ...

Intra-operative quality assurance and dosimetry optimization in prostate brachytherapy critically depends on the ability of discerning the locations of implanted seeds. Various methods exist for seed matching and reconstruction from multiple segmented C-arm images. Unfortunately, using three or more images makes the problem NP-hard, i.e. no polynomial-time algorithm can provably compute the com...

Oxygen evolution reaction (OER) and hydrogen (HER) are the key processes in water splitting. Compared with two-electron process HER, four-electron of OER is slow because more complex series reactions. Therefore, a good understanding direct O2 mechanism (DOEM) crucial to design high-efficiency catalysts overcome limitations imposed by conventional adsorption mechanism. In this work, honeycomb Ni...

BACKGROUND Numerous techniques have been used to treat acromioclavicular (AC) joint dislocation, with anatomic reconstruction of the coracoclavicular (CC) ligaments becoming a popular method of fixation. Anatomic CC ligament reconstruction is commonly performed with cortical fixation buttons (CFBs) or tendon grafts (TGs). PURPOSE To report and compare short-term complications associated with ...

Weak protein interactions between ubiquitin and the ubiquitin-proteasome system (UPS) enzymes that mediate its covalent attachment to substrates serve to position ubiquitin for optimal catalytic transfer. We show that a small-molecule inhibitor of the E2 ubiquitin-conjugating enzyme Cdc34A, called CC0651, acts by trapping a weak interaction between ubiquitin and the E2 donor ubiquitin-binding s...

1 Faculty of Science, Sokoine University of Agriculture, P. O. Box 3038, Solomon Mahlangu Campus, Morogoro, Tanzania. 2 Faculty of Veterinary Medicine, Sokoine University of Agriculture, P. O. Box 3015, Chuo Kikuu, Morogoro, Tanzania. 3 Instute of Traditional medicine Department of Natural Product Development and Formulation, Muhimbili University of Health and Applied Sciences, P.O. Box 65001 D...

BACKGROUND Although autologous fat grafting is widely accepted for breast reconstruction, its indications remain limited to minor contour deformities after reconstruction and small deformities after breast-conserving surgery. The authors describe a case series of total or nearly total breast reconstructions treated with the perioperative use of a vacuum-based external tissue expander (i.e., the...

BACKGROUND We present a novel method for augmenting the standard C-V flap used for nipple reconstruction with a free dermal graft which aims to improve the appearance of the nipple reconstruction, decrease loss of projection and improve patient satisfaction overall. METHODS The surgical technique for performing a free dermal graft augmentation of a CV flap is described. All patients who under...