The post-translational modification of proteins provides a rapid and versatile system for regulating all signalling pathways. Protein ubiquitination is one such type of post-translational modification involved in controlling numerous cellular processes. The unique ability of ubiquitin to form polyubiquitin chains creates a highly complex code responsible for different subsequent signalling outc...

cellular manufacturing system (cms) is highly important in modern manufacturing methods. given the ever increasing market competition in terms of time and cost of manufacturing, we need models to decrease the cost and time of manufacturing. in this study, cms is considered in condition of dynamic demand in each period. the model is developed for facing dynamic demand that increases the cost of ...

Introduction: During nephrogenesis, transition of mesenchyme to the epithelium of tubules and glomeruli occurs via the interaction of ureteral bud and metanephric mesenchyme. The distribution pattern of collagen type IV suggests that a regulated balance of activities is required to facilitate migration of the ureteral bud branches into the mesenchyme and to control early extracellular matrix ch...

Gustave Roussy Cancer Campus; Villejuif, France; Equipe 11 labellis ee par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers; Paris, France; Universit e Paris Descartes/Paris V; Sorbonne Paris Cit e; Paris, France; INSERM, UMS1138; Paris, France; Pôle de Biologie, Hôpital Europ een Georges Pompidou, AP-HP; Paris, France; Metabolomics and Cell Biology Platforms, Gustave Rou...