The HIV-1 Vif protein suppresses the inhibition of viral replication caused by the human antiretroviral factor APOBEC3G. As a result, HIV-1 mutants that do not express the Vif protein are replication incompetent in 'nonpermissive' cells, such as primary T cells and the T-cell line CEM, that express APOBEC3G. In contrast, Vif-defective HIV-1 replicates effectively in 'permissive' cell lines, suc...

The Multi-Input Multi-Output (MIMO)Constant Envelope Modulation MIMOCEM is introduced as power and complexity efficient alternative to MIMO-OFDM for wireless backhaul networks. Due to a low resolution ADC (1-bit in the default operation) employed in the MIMO-CEM receiver, MIMO-CEM channel estimation is considered as one of the major challenges toward its real application. A block based adaptive...

Multidrug resistance is a major obstacle to the success of cancer chemotherapy. The multidrug resistance-associated protein (MRP) has been shown to confer multidrug resistance. To study MRP gene expression at the transcriptional level, we have fused the MRP gene promoter with the luciferase reporter gene and studied its regulation. Cotransfection of MRP promoter constructs with p53 expression p...

INTRODUCTION The aim of the present study was to evaluate whether adding 2% chlorhexidine (CHX) and 2.6% sodium hypochlorite (NaOCl) to calcium-enriched mixture (CEM) cement would affect its setting time (ST), or not. METHODS AND MATERIALS In this study, the setting time of CEM cement was evaluated in three groups (n=9) as follows: group 1; CEM cement, group 2; CEM cement+2% CHX and group 3; ...

In the context of chronic childhood emotional maltreatment (CEM; emotional abuse and/or neglect), adequately responding to facial expressions is an important skill. Over time, however, this adaptive response may lead to a persistent vigilance for emotional facial expressions. The amygdala and the medial prefrontal cortex (mPFC) are key regions in face processing. However, the neurobiological co...