background : primary central nervous system involvement and central nervous system relapse are poor prognostic events in acute lymphoblastic leukemia. due to severe skeletal and endocrine complications of craniospinal radiotherapy, only cranial radiotherapy is advisable. however only 15% of the cases with central nervous system relapse may remain in remission; a second central nervous system or...

drug-in-adhesive transdermal drug delivery systems  )tddss) containing stimulants, termed as energetic substances, such as caffeine and pantothenic acid, were studied. caffeine is a white crystalline substance and a stimulant to central nervous system. in humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. pantothenic acid, al...

Background & Objectives: The accurate assessment of the diseased tissue is fundamental to the diagnosis and management of disorders of the central nervous system (CNS). The ‛squash’ or ‛crush’ technique has been universally employed in the intraoperative diagnosis of CNS tumors. The aim of our study was to evaluate the accuracy of squash preparation in diagnosing CNS tumors by comparing with hi...

Dental professionals should be aware that methamphetamine (MA) use is on the rise in North America. MA is a potent central nervous system stimulant with limited therapeutic effects. The allure of this drug is its availability in many different forms that are relatively easy to make and distribute and inexpensive to purchase and that produce prolonged euphoria for the user. This euphoria results...

Caffeine and dietary supplements have been shown to play a role in the regulation and circulation of blood. If taken in excessive amounts, they may cause damage to the circulatory system or heart. To test the effects for myself, I administered both caffeine and dietary supplements on water organisms, specifically daphnia. The results for caffeine turned out as expected and further proved the ef...

Information on the rates and predictors of polypharmacy of central nervous system medication in older people with intellectual disability is limited, despite the increased life expectancy of this group. This study examined central nervous system medication use in an older sample of people with intellectual disability. Data regarding demographics, psychiatric diagnoses and current medications we...

Fluoxetine is a selective serotonin reuptake inhibitor that increases serotonin concentration in the central nervous system and modulates various systems, including the control of sympathetic outflow and the hypothalamus-pituitary-adrenal. However, it is not yet established whether fluoxetine can modulate the responses to stressors stimulants (physical or chemical) that trigger cortisol respons...

background : labeling, gathering mutual information, clustering and classification of central nervous system tumors may assist in predicting not only distinct diagnoses based on tumor-specific features but also prognosis. this study evaluates the epidemi- ological features of central nervous system tumors in children who referred to mahak’s pediatric cancer treatment and research center in tehr...

OBJECTIVES Case reports have raised concerns about the risk of cardiac events associated with central nervous system stimulants for the treatment of attention-deficit/hyperactivity disorder. PATIENTS AND METHODS This was a retrospective cohort study that used 10 years (July 1994 to June 2004) of Florida Medicaid claims data cross-linked to Vital Statistics Death Registry data. The cohort was ...