نتایج جستجو برای: ceramidase

تعداد نتایج: 515  

2014
E. Ellen Jones Shaalee Dworski Daniel Canals Josefina Casas Gemma Fabrias Drew Schoenling Thierry Levade Chadrick Denlinger Yusuf A. Hannun Jeffrey A. Medin Richard R. Drake

A novel MALDI-FTICR imaging mass spectrometry (MALDI-IMS) workflow is described for on-tissue detection, spatial localization, and structural confirmation of low abundance bioactive ceramides and other sphingolipids. Increasingly, altered or elevated levels of sphingolipids, sphingolipid metabolites, and sphingolipid metabolizing enzymes have been associated with a variety of disorders such as ...

2018
Sakayu SHiMizu

sphingosine from ceramides by ceramidase, and the production of sphingosine-l-phosphate from sphingosine by sphingosine kinase. The most abundant types of SM and Cer have structures 1 and 2, respectively, in which the amino nitrogen beqrs a palmitoyl grQup. It has redently b6en demoristrated bY Takahata') that, by incubating PC 12 cells with docosahexaenoic acid (DHA)-abundant fish oil, the pal...

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