This work focuses on exploration of the potential use of pulsatile brain bioimpedance (rheoencephalography REG) measurement as a non-invasive, continuous method for assessing the status of cerebral blood flow (CBF) in combat casualties.

A basic understanding of how anaesthesia affects cerebral blood flow and cerebral metabolism is readily available as common textbookmaterial [1]. In general, most anaesthetic agents decrease cerebralmetabolism in a dose-dependentmannerwith variable effects on cerebral blood flow [2]. Despite a basic understanding of the cerebral effects of anaesthetics, the study of anaesthetic effects on cereb...

A technique is described for the production of subarachnoid haemorrhage in baboons and their subsequent recovery for chronic study of cerebrovascular reactivity. The baboons make complete neurological recoveries but the response of their cerebral circulation to hypercapnia is impaired one week later. Baseline values of cerebral blood flow and of cerebral oxygen consumption are unaffected at thi...

The new knowledge and clearer concepts of the pathogenesis of cerebrovascular disease and of "order and disorder" in the cerebral circulation acquired in recent years have improved the possibilities of treatment, which may now be considered at four stages in the evolution of a stroke: by prevention, when factors contributing to "stroke-proneness" may be identified and offset; by anticipation of...

We derive a two-layer multiplex Kuramoto model from Wilson-Cowan type physiological equations that describe neural activity on a network of interconnected cortical regions. This is mathematically possible due to the existence of a unique, stable limit cycle, weak coupling, and inhibitory synaptic time delays. We study the phase diagram of this model numerically as a function of the inter-region...

This paper presents an approach to characterizing evoked hemodynamic responses in fMRI based on nonlinear system identification, in particular the use of Volterra series. The approach employed enables one to estimate Volterra kernels that describe the relationship between stimulus presentation and the hemodynamic responses that ensue. Volterra series are essentially high-order extensions of lin...