There is an urgent need to develop data integration and testing strategy frameworks allowing interpretation of results from animal alternative test batteries. To this end, we developed a Bayesian Network Integrated Testing Strategy (BN ITS) with the goal to estimate skin sensitization hazard as a test case of previously developed concepts (Jaworska et al., 2010). The BN ITS combines in silico, ...

TITLE OF THE TEST GUIDELINES (YEAR OF APPROVAL): In Chemico Skin Sensitisation: Direct Peptide Reactivity Assay (DPRA), OECD 442C (adopted 2015) In Vitro Skin Sensitisation: ARE-Nrf2 Luciferase Test Method, OECD 442D (adopted 2015) In Vitro Skin Sensitisation: Human Cell Line Activation Test (h-CLAT) (draft OECD TG under discussion, EURL ECVAM recommendation published 2015) In vivo tests: Skin ...

Aim of this research was to study the effect of some agronomic and oenological factors on the content of biogenic amines as quality index of sixty-five Abruzzo wines. Sum of amines was found to be decreasing in the order: red (19.3±12.8mgL(-1)), rosé (9.20±6.34mgL(-1)), white (7.67±3.84mgL(-1)) wine. Significant differences in relationship among amines levels and chemical and chemico-physical c...

To develop an active biopolymer film based on chitosan, sodium caseinate, and rosemary essential oil (REO), the objective of this work was to investigate effect REO structure physical properties films. Fourier transform infrared spectroscopy conducted for fingerprinting identify addition. The thermal behaviour each investigated using a thermogravimetric analysis. Furthermore, optical properties...

Aim of this work is to analyze the coronavirus viral surface properties related pattern electrical features. This chemical physical property relevant and crucial set profile diffusion, severity disease, efficacy therapeutic strategy in order search new way fight COVID-19 NEW VARIANT. The phenomena immune evasion different towards variants some vaccine or antibodies combination produce need veri...

In the last decade, extensive studies have been conducted to quantify influence of different factors on potentially toxic elements (PTE) bioaccessibility in soil; one most important is soil size fraction. However, there no agreement about fraction and methods investigate bioaccessibility, as very few review articles are available PTE none addressed particle bioaccessibility. This study provides...

Hydrophobic treatment is one of the most important interventions usually carried out for conservation stone artefacts and monuments. The study here reported aims to answer a general question about how two polymers confer different protective performance. Two fluorinated-based polymer formulates applied on samples Cusa’s level water repellence vapour permeability. observed protection action expl...