The input buffers of the current packet-switched Network-on-Chip (NoC) architectures consume a significant portion of the total power of the interconnection network. Reducing the size of input buffers would result in degraded performance, while eliminating all buffers would result in increased power at high network load. In this article, we propose DXbar: an innovative dual-crossbar design. By ...

ChIP-seq datasets provide a wealth of information for the identification of candidate regulatory elements in the genome. For this potential to be fully realized, methods for evaluating data quality and for distinguishing reproducible signal from technical and biological noise are necessary. Here, the computational methods for addressing these challenges developed by the ENCODE Consortium are de...

Tiling arrays make possible a large-scale exploration of the genome thanks to probes which cover the whole genome with very high density, up to 2,000,000 probes. Biological questions usually addressed are either the expression difference between two conditions or the detection of transcribed regions. In this work, we propose to consider both questions simultaneously as an unsupervised classific...

A concept for solving the communication problem among modules dynamically placed on a reconfigurable device is presented. Based on a dynamic network-on-chip (DyNoC) communication infrastructure, components placed at run-time on a device can mutually communicate. A 4x4 dynamic network-on-chip communication infrastructure prototype, implemented in an FPGA occupies only 7% of the device area and c...

Genome-wide ChIP-chip assays of protein-DNA interactions yield large volumes of data requiring effective statistical analysis to obtain reliable results. Successful analysis methods need to be tailored to platform specific characteristics such as probe density, genome coverage, and the nature of the controls. We describe the use of the respective software packages MAT and MA2C for the analysis ...

Abstract Superconducting digital circuits are a promising approach to build integrated systems with high energy-efficiency and computational density of the packaged chips. In such systems, performance data link between chips mounted on multi-chip-module (MCM) is critical driver performance. this work we report synchronous using reciprocal quantum logic enabled by resonant clock distribution on-...

This document describes the BCRANK R package. BCRANK[1] is a method that takes a ranked list of genomic regions as input and outputs short DNA sequences that are overrepresented in some part of the list. The algorithm was developed for detecting transcription factor (TF) binding sites in a large number of enriched regions from high-throughput ChIP-chip or ChIP-seq experiments, but it can be app...