BACKGROUND Investigation of new effective drugs against the methicillin-resistant strains of Staphylococcus aureus (MRSA) is an urgent issue of modern medicine. Antiseptics as an alternative of antibiotics are strong, sustained, and active preparations against resistant strains and do not violate microbiocenosis. MATERIALS AND METHODS The activity of in situ prepared chitosan-Ag nanoparticles...

Biopolymer blends between collagen and chitosan have the potential to produce cell scaffolds with biocompatible properties. In this study, porous scaffolds were fabricated by freeze drying the solution of collagen and chitosan and crosslinked by dehydrothermal treatment (DHT). Various types of scaffolds were prepared by varying compositions of collagen and chitosan. The scaffolds were fully cha...

Two different deacetylated chitosans were dissolved in formic, acetic, lactic, or propionic acid to prepare chitosan films. The pH values of the film-forming solutions were adjusted to 3, 4, and 5. Water vapor permeability (WVP), tensile strength (TS), elongation (E), and total soluble matter (TSM) were significantly (P < 0.05) affected by acid type, pH, and degree of deacetylation (DA). Low DA...

This study presents the first ever data of extracting chitin from the Chiton shell, which then converted to the soluble chitosan by soaking in the 45% NaOH solution. The obtained chitin and chitosan were characterized by the seven different methods. Antioxidant activity of the extracted chitosan was also evaluated using the two methods. The shell content was divided into calcium carbonate (90.5...

background gelatin and chitosan are known as biodegradable and biocompatible biopolymers.these biopolymers have recently receivedincreasingly more attention for tissueengineering.the aim of this study was to evaluate the toxicity effects of gelatin-chitosan film on bone marrow stromal cell(bmscs) culture in rat.                                                  material & methods: first, gelatin...

Chitin a natural polymer extracted commercially from the shells of crustaceans such as prawns, crabs, krill, insects and shrimps. Chitosan is prepared from chitin by partially deacylating its acetamido groups with a strong alkaline solution. Chitin and chitosan have a wide variety of applications such as wastewater treatment which decreases the Chemical Oxygen Demand [COD] and used in preventin...

A new method was developed for marine harmful algal bloom (HAB) mitigation using local beach sand or silica sand modified with chitosan and polyaluminum chloride (PAC). Untreated sand was ineffective in flocculating algal cells, but 80% removal efficiency was achieved for Amphidinium carterae Hulburt and a Chlorella sp. in 3 min (t80 = 3 min) using 120 mg L-1 sand modified with 10 mg L-1 PAC an...

Chitosan is a polysaccharide composed of randomly distributed chains of β-(1-4) D-glucosamine and N-acetyl-D-glucosamine. This compound is obtained by partial or total deacetylation of chitin in acidic solution. The chitosan-based hemostatic agents have been gaining much attention in the management of bleeding. The aim of this study was to evaluate in vitro hemagglutination activity of chitosan...

Phenol derivative-containing adhesive hydrogels has been widely recognized as having potential for biomedical applications, but their conventional production methods, utilizing a moderate/strong base, alkaline buffers, the addition of oxidizing agents or the use of enzymes, require alternative approaches to improve their biocompatibility. In this study, we report a polymeric, enzyme-mimetic bio...

The purpose of this study was to investigate the antibacterial activity of calcium hydroxide [Ca(OH)2] combined with chitosan solutions against Enterococcus faecalis-infected root canal dentin and the effect of this new intracanal medicament on the bond strength of RealSeal sealer to radicular dentin. An experimental intracanal medicament was prepared by mixing different concentrations of chito...