Ion channels are known to be present on the plasma membrane of virtually all cells and have been found on the membranes of various intracellular organelles. However, until recently they were believed not to occur at the nuclear membrane. In this study we describe the molecular cloning and characterization of a nuclear ion channel protein, designated nuclear chloride channel-27 (NCC27), from the...

Thermal gradients induce concentration gradients in alkali halide solutions, and the salt migrates towards hot or cold regions depending on the average temperature of the solution. This effect has been interpreted using the heat of transport, which provides a route to rationalize thermophoretic phenomena. Early theories provide estimates of the heat of transport at infinite dilution. These valu...

The mechanism responsible for active sodium transport in the urinary bladder of the toad appears to be located at the serosal boundary of the epithelial cell layer of the bladder. Studies of the potential step observed at the serosal boundary in the open-circuited state were undertaken in an attempt to define the factors responsible for its production. Glass micropipettes were used to measure t...

STEVENS, CHARLES E. Transport of sodium and chloride by the isolated rumen epithelium. Am. J. Physiol. 206(5) : 1099-I 105. I g64.-Transepithelial electrical potential, short-circuit current, and resistance measurements were made under different conditions of tissue collection and maintenance. The collection procedure greatly affected tissue resistance and, since the magnitude of the current wa...

An investigation was undertaken to study the factors which cause grossly elevated values in an automated procedure for chloride when the sample is contaminated with bromide. The questioned mercuric thiocyanate method of the autoanalyzer was compared to a similar system utilizing mercuric 2, 4, 6-tripyridyl-s-triazine as a substitute ligand source in the chloride exchange system. It was determin...

The designed service life of Hong Kong-Zhuhai-Macao Bridge is 120 years. Concrete quality control for the submerged tunnel of the project is an important work to assure the designed service life. This article is to present an advanced concrete performance prediction method based on water–binder ratio (w/b) monitoring, which is used to serve for concrete quality control. During experiments in th...

To evaluate the chloride ion corrosion resistance of proposed innovative self-healing concrete based on shape memory alloys (SMA) and engineering cementitious composites (ECC), a total 2 kinds 22 specimens were prepared. Chloride tests SMA-ECC under dry-wet cycles carried out. It was found that erosion depths significantly smaller than MC, growth rate depth obviously MC after 15 (dry wet) cycle...

    Electrochemical aptamer-based sensors attract a lot of interest as useful methods because of their low cost, accuracy, sensitivity, and simplicity. An electro-active redox molecule comprises the main part of the electrochemical-based sensors. Ferrocene is one of the most popular redox molecule used in biosensor fabrication. But, instability of ferrocenium ion in strong nucleophilic reagents...