BACKGROUND The pathogenesis of total joint replacement failure is multifactorial. One hypothesis suggests that corrosion and wear of alloys result in metal ion release, which may then cause sensitization and even implant failure, owing to the acquired immune reactivity. OBJECTIVES To assess cobalt, nickel and chromium(VI) release from, and the metal composition of, failed metal-on-ethylene to...

In the title compound, [Cr(2)Nd(2)F(4)(NO(2))(8)(C(12)H(8)N(2))(4)]·4CH(3)OH·H(2)O, two cis-difluoridobis(1,10-phenanthroline)chromium(III) fragments containing octa-hedrally coordinated chromium(III) bridge via fluoride ions to two tetra-nitratoneodymate(III) fragments, forming an uncharged tetra-nuclear square-like core. The fluoride bridges are fairly linear, with Cr-F-Nd angles of 168.74 (8...

Individuals with advanced hip disease suffer from pain, impaired hip function, and decreased quality of life. Roughly one million metal-on-metal (MoM) hip prostheses have been implanted worldwide in order to ameliorate these issues. While most MoM hip replacements are successful, some patients suffer from serious adverse effects secondary to the release of metal debris due to implant wear and c...

Metal ions generated from joint replacements are a cause for concern. There is no consensus on the best surrogate measure of metal ion exposure. This study investigates whether serum and whole blood concentrations can be used interchangeably to report results of cobalt and chromium ion concentrations. Concentrations of serum and whole blood were analysed in 262 concurrent specimens using high r...

This paper utilizes data from two pilot studies conducted at Superfund Sites to discuss the electrochemical iron addition process developed by Andco Environmental Processes, Inc. Electrical current and steel electrodes were used to put ferrous and hydroxyl ions into solution. Once added, the chemistry was properly manipulated to provide coprecipitation and adsorption conditions capable of simul...

Blood metal ions have been widely used to investigate metal-on-metal hip replacements, but their ability to discriminate between well-functioning and failed hips is not known. The Medicines and Healthcare products Regulatory Agency (MHRA) has suggested a cut-off level of 7 parts per billion (ppb). We performed a pair-matched, case-control study to investigate the sensitivity and specificity of ...

Poly(1,3-thiazol-2-yl methacrylamide-co-4-vinyl pyridine-co-divinylbenzene) was prepared and used as a sorbent for the solid-phase extraction of Cr(VI) ions from aqueous solution. Two forms of chromium showed different exchange capacities at different pH values; Cr(VI) was selectively retained especially at pH 2. The total chromium was determined after the oxidization of Cr(III) to Cr(VI) by po...