background chronic rhinosinusitis (crs) and asthma are among the most important health-related conditions with evident socio-economic effects. the relationship between asthma and crs has been considered in medical references for centuries. previous studies have shown that treatment interventions targeting disease in one part of the airway are effective for general asthma management. however, th...

introduction: anthroponotic cutaneous leishmaniasis (acl) is still a major public health problem in the northeast and central parts of iran. this study was designed to compare microscopy and cultivation methods with pcr amplification of kinetoplast dna and its1 followed by rflp analysis for diagnosis of acute and chronic acl. methods: in this study, 66 patients with acl including 24 acute and 4...

background: non-communicable diseases (ncds) annually kill over 35 million people worldwide. they are responsible for nearly two-thirds of the world's deaths. global health is facing a dramatic change. for the first time in human history, more than 80% of ncd-related deaths are in low- and middle-income countries. countries throughout the world are expected to lose significant amounts of nation...

background: nasal inflammatory disorders such as chronic rhinosinusitis and nasal polyp are among the most prevalent complications with high socioeconomic costs. vascular endothelial growth factor (vegf) plays a key role in angiogenesis and cell proliferation. in the present study the effect of vegf on the development and prognosis of chronic rhinosinusitis and nasal polyp was investigated. met...

this preliminary study was designed to evaluate the effects of heberon alfa for the treatment of chronic hepatitis b infected subjects in iran. a single center, open label, single treatment prospective study of interferon alfa (heberon alfa), 5 million units every other day for a period of 4 months, was performed between 1996 to 1998. a total number of 30 patients with histologically documented...

background chronic rhinosinusitis is an inflammatory-infectious disease involved paranasal sinuses as a common site of microbial pathogens and infections in patients suffering from the disease. the disease is labeled chronic when it lasts for more than 12 weeks. objectives as these infections constitute an important cause of morbidity it can be a strong life-threatening factor, in this investig...

introduction: the efficiency of routine scaling and root planning is negatively influenced by the tooth anatomy and residual bacteria all possibly affecting the treatment outcomes in future. the present study compared the microbiologic effectiveness of the photodynamic therapy (pdt) as an adjunctive treatment modality for nonsurgical treatment in chronic periodontitis. methods: in this randomiz...

background chronic kidney disease (ckd) is a prevalent, progressive, and treatable disease. however, lack of enough data about its prevalence in iran is a major obstacle for its early detection. in order to determine the prevalence of the disease in the country, it is necessary to conduct epidemiologic studies especially on populations with ethnic diversity; hence, this study aimed at determini...