bronchial responsiveness to bronchodilator medications is usually tested to establish reversibility of airflow obstruction. among the various tests to establish bronchodilator response, fev1, fef25-75% or fef50%, and fvc are the most widely used. in a cross-sectional study, we assessed spirometric responses after administration of bronchodilator in 187 workers with obstructive pattern in spirom...

the use of flow cytometry in the clinical laboratory has grown substantially in the past decade. flow cytometric analysis provides a rapid qualitative and quantitative description of multiple characteristics of individual cells. for example, it is possible to detect the cell size and granularity, aspects of dna and rna content and the presence of cell surface and nuclear markers which are used ...

BACKGROUND Episodic breathlessness is one form of refractory breathlessness. Better understanding of the symptom is necessary for effective management. AIM The aim was to describe the characteristics of episodic breathlessness in patients with advanced chronic obstructive pulmonary disease or lung cancer. DESIGN This is a longitudinal cohort study. Outcomes were assessed monthly by up to 13...

Introduction The true prevalence of chronic suppurative lung disease (CSLD) and other respiratory illness in Indigenous children is unknown. There is however little doubt that the burden of CSLD is disproportionately high in remote and rural Indigenous communities. In Central Australia the prevalence of high resolution computed tomography (HRCT) proven bronchiectasis in children (<15 years) is ...

background: chronic obstructive pulmonary disease (copd) is a major public health problem worldwide. smoking is the number one cause of copd; however, genetic, environmental and dietary factors contribute to the etiology of this disease. in this study, we assessed the association between three diet quality indices -the healthy eating index-2005 (hei-2005), the healthy eating index-2010 (hei-201...

Pericytes are mesenchymal cells embedded within the abluminal surface of the endothelium of microvessels such as capillaries, pre-capillary arterioles, post-capillary and collecting venules, where they maintain microvascular homeostasis and participate in angiogenesis. In addition to their roles in supporting the vasculature and facilitating leukocyte extravasation, pericytes have been recently...

Chronic obstructive pulmonary disease (COPD) is characterized by tissue loss and a growing restriction of airflow. Due to chronic inflammation brought on extended exposure noxious particles or gases, most often cigarette smoke, it linked structural abnormalities in the lungs. Airway constriction reduction lung recoil are results inflammation. In affluent countries, majority COPD cases caused to...

Background and Purpose: Chronic granulomatous disease (CGD) is an inherited disorder of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. This disorder results in recurrent life-threatening bacterial and fungal infections. Aspergillus species are the most common fungal infections in these patients. Case Report: Herein, we present a case of fungal infection in a girl wi...